Hypersensitivity

Question 1

Allergy definition

Answer 1

inflammatory response that is unwanted or inappropriate

Question 2

Immune mediated hypersensitivity definition

Answer 2

an inflammatory response to an antigen that is inappropriate bc:

• antigen is not part of a pathogen ex. pollen
• excessive inflammation damages host more than pathogen
• may be site specific or whole body
• severe = anaphylactic shock

Question 3

Antigen

Answer 3

causes allergic response

Question 4

Four types of immune hypersensitivity

Answer 4

1 - activated by Ige
2 - IgG or IgM bind to normal tissue
3 - antibody - antigen complexes activate immune response
4 - T cells and macrophages directly cause inflammation