Hypersenitivity Pneumonitis

Question 1

another name for hypersensitivity pneumonitis

Answer 1

extrinsic allergic alveolitis

inflammatory response to inhaled antigens affect alveoli and small airways

Question 2

true or false.smokers are more prone to develop HP

Answer 2

false.

there is an unexplained decreased risk in smokers

Question 3

the type of established immunologic mechanism seen in HP

Answer 3

immune complex mediated reaction

inflammatory pattern: involves TH1

Question 4

seen with continued low level antigen exposure or repeated episodes
irreversible respiratory impairment NOT responsive to removal of antigen

Answer 4

chronic form HP

Question 5

occurs 4-8 hours after exposure of antigen

resolves within hours to a few days

Answer 5

acute form of HP

Question 6

what are the 6 predictors of HP

Answer 6

1. exposure to known antigen
2. presence of serum precipitins
3. recurrent symptoms
4. inspiratory crackles
5. symptoms after 4-8 hrs after exposure
6. weight loss

Question 7

mainstay treatment for HP

Answer 7

antigen avoidance

Question 8

type of HP where PROMPT Glucocorticoids are needed for relief of symptoms

Answer 8

subacute HP
prednisone 0.5 - 1 mkd for 1-2 weeks, then taper over next 2-6 weeks

acute HP - no role
chronic HP - trial of glucocorticoid

Question 9

antigen: penicillum casei, aspergillus clavatus

Answer 9

cheese washer’s lung

Question 10

thermophilic actinomycetes, mushroom spores

Answer 10

mushroom worker’s lung

Question 11

antigen: sitophilus granarius

Answer 11

miller’s lung

Question 12

antigen: cladosporium species, mycobacterium avium complex

Answer 12

hot tub lung

Question 13

antigen: bacillus subtilis

Answer 13

detergent worker’s lung