Hyperparathyroidism and Hypoparathyroidism Flashcards
1
Q
Causes of hypercalcaemia?
A
- Medications (e.g., calcium and vitamin D supplements)
- Hyperparathyroidism
- Cancer ( esp. lung, breast and kidney)
- Renal failure with reduced calcium excretion
2
Q
How to treat hypercalcaemia caused by cancer? Mechanism of action?
A
SC or IM calcitonin
Inhibits osteoclast activity and calcium reabsorption in the kidneys
3
Q
Management of primary hyperparathyroidism
A
Medical: Cinacalcet
Surgery
4
Q
What is secondary hyperparathyrodism
A
High PTH due to…
Vitamin D deficiency or CKD causes hypocalcaemia -> PT gland compensates by producing too much PTH
4
Q
What is tertiary hyperparathyroidism
A
High PTH due to…
Secondary hyperparathyroidism even after correction of vit D/CKD as PT hormones have undergone hyperplasia and continues secreting too much PTH
