Hyperparathyroidism Flashcards
What are the 2 most common causes of primary hyperparathyroidism. Which of them is more common?
What essential investigations (unlike the medicine chapter) should you order (along with expected results for all)
Multiple glands = parathyroid hyperplasia
Go through the lab results you expect in primary, secondary and tertiary hyperparathyroidism
+
Mention the most common reason behind each
A patient with known parathyroid hyperplasia presents with acute abdominal pain. Im being vague on purpose. What is the most likely acute abdominal presentation?
You decide to perform reflexes on this patient. What do you expect to find?
Pancreatitis secondary to hypercalcaemia
Reduced depp tendon reflexes bilaterally
What symptoms would patients with a hyperparathyroidism secondary to a solitary nodule present with?
What is the management of acute Hypercalcaemia?
How does it differ from a patient presenting with acute hypercalcaemia that has just been diagnosed with a solitary nodule of the parathyroid gland?
Note: Include escalations
Know this algorithm well, exactly as shown in the picture. Mention the part with bisphosphonates and then mention how it should be avoided if surgery is anticipated
State the management of secondary and tertiary hyperparathyroidism
A patient presenting with signs and symptoms of hypercalcemia but US parathyroid and sestamibi scan are negative for anything. The patient has no history of CKD.
What are your top 3 differentials?
Familial hypocalciuric hypercalcemia
Vitamin D deficiency/malabsorption (crohn’s and Coeliac, short bowel syndrome)
PTHrP is secreted by
Small cell lung Ca
Breast Ca
RCC (i said CKD)
