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METABOLIC AND ENDOCRINE > Hyperparathyroid > Flashcards

Hyperparathyroid Flashcards

1
Q

Clinical Features

A

Bone pain, fragility fractures, ↓BMD
Nephrolithiasis, Nephrocalcinosis, polyuria, renal insufficiency
Nausea, Vomiting, PUD, constipation, pancreatitis
Lethargy, decreased cognition, depressed mood, psychosis, coma
Gout, pseudo gout
LV Hypertrophy, ↓QT interval

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2
Q

DDx

A

Vit D Deficiency
Chronic Renal Insufficiency
TSH
Malignancy
Adrenal Insufficiency

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3
Q

Risk Factors

A

Age > 50
F > M
Meds: Thiazide, Lithium
Radiation to neck, radioactive iodine
Genetic: MEN Type 1 + Type 2A, Familial Hypocalciuric Hypercalcemia, Familial Hyperparathyroidism – jaw tumor syndrome, Neonate severe hyperparathyroidism, Familial isolated hyperparathyroidism

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4
Q

Investigations

A

PTH
Ca
Albumin

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5
Q

Management of Primary Hyperparathyroidism

A

Volume Repletion
Loop Diuretics once euvolemic
Pamidronate or Zolindronate
Parathyroidectomy

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METABOLIC AND ENDOCRINE (17 decks)

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