hyperlipidemia Flashcards

1
Q

standard cholesterol levels

A

total <200
LDL <100
HDL>60

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2
Q

standard TG levels

A

<150

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3
Q

what are some good fats

A

mono/polyunsaturated (omegas) fats

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4
Q

moderate vs high dose statins effect LDL by how much

A

30-50%

>50%

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5
Q

best statin options

A

atorvastatin

rosuvastatin

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6
Q

can you use statins during pregnancy?

A

no, put back on after pregnancy

also C/I in active hepatic disease

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7
Q

Bile sequestering agents

A

cholestyramine

colestipol

colesevelam

C/I in hypertriglyceridemia

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8
Q

fibric acid derivitives

A

gemfibrozil
fenofibrate
Primarily used to treat hypertriglyceridemia or marked HDL deficiency

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9
Q

nicotinic acid (niacin)

A
  • lowers TGs

- flushing

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10
Q

fish oils are useful for….

A

lowering TGs

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11
Q

icosapent ethyl

A

adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia

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12
Q

ATP panel recommendations for tx

A

1) with clinical ASCVD
2) primary elevations of LDL–C >190 mg/dL
3) diabetes aged 40 to 75 years with LDL–C 70 to189 mg/dL and without clinical ASCVD
4) without clinical ASCVD or diabetes with LDL–C 70 to189 mg/dL and estimated 10-year ASCVD risk >7.5%

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13
Q

ADRs of statins

A
  • hepatotoxicity
  • myalgia, rhabdo
  • decreased cognitive function
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