hyperlipidemia Flashcards
standard cholesterol levels
total <200
LDL <100
HDL>60
standard TG levels
<150
what are some good fats
mono/polyunsaturated (omegas) fats
moderate vs high dose statins effect LDL by how much
30-50%
>50%
best statin options
atorvastatin
rosuvastatin
can you use statins during pregnancy?
no, put back on after pregnancy
also C/I in active hepatic disease
Bile sequestering agents
cholestyramine
colestipol
colesevelam
C/I in hypertriglyceridemia
fibric acid derivitives
gemfibrozil
fenofibrate
Primarily used to treat hypertriglyceridemia or marked HDL deficiency
nicotinic acid (niacin)
- lowers TGs
- flushing
fish oils are useful for….
lowering TGs
icosapent ethyl
adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia
ATP panel recommendations for tx
1) with clinical ASCVD
2) primary elevations of LDL–C >190 mg/dL
3) diabetes aged 40 to 75 years with LDL–C 70 to189 mg/dL and without clinical ASCVD
4) without clinical ASCVD or diabetes with LDL–C 70 to189 mg/dL and estimated 10-year ASCVD risk >7.5%
ADRs of statins
- hepatotoxicity
- myalgia, rhabdo
- decreased cognitive function