Hyperleukocytosis Flashcards

1
Q

Define hyperleukocytosis?

A

White cell count >100 x 10^9

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2
Q

neurological S&S of hyperleukocytosis

A

stroke, HA, altered LOC

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3
Q

Resp S&S of hyperleukocytosis

A

hypoxia, dyspnea

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4
Q

hemorrhagic S&S of hyperleukocytosis

A

CNS, GI, pulmonary

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5
Q

renal S&S of hyperleukocytosis

A

Renal failure

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6
Q

Metabolic S&S of hyperleukocytosis

A

tumour lysis syndrome

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7
Q

what are the treatment principles of hyperleukocytosis?

A

close obs ?ICU, increase fluids to 1.5 - 2x maintenance, monitor output, correct coagulopathy target plt 30 - 50, avoid prbc transfusion, tumour lysis precaution, early chemo,

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