Hyperemesis gravidarum

Question 1

Define Hyperemesis gravidarum

Answer 1

N&V in early pregnany are so severe so to cause severe dehydration, weight loss or electrolyte disturbance

Question 2

Outline the epidemiology of Hyperemesis gravidarum

Answer 2

1 in 750

N&V common, however most at mildly/ moderately dehydrated and so have “mild/ moderate N&V of prenancy (NVP)”

Seldom past 14wks

More common in multiparous women

Question 3

Outline the management of mild & moderate NVP & Hyperemesis gravidarum

Answer 3

• Mild NVP
  
  • Non required
• Moderate NVP
  
  • Often admitted
• Hyperemesis gravidarum
  
  • Admitted
  • Intravenous rehydration
  • Antiemetics: metoclopramide, cyclizine & ondansetron
  • Thiamine [prevention]
  • Psychological support