Hydrophobic Signals and control of transcription Flashcards
Where can
Hydrophobic signalling molecules
diffuse
Directly through the phospholipid bilayer of membranes
Pathway of
Hydrophobic signalling molecules
Diffuse through the PBiylayer and bind to intracellular receptors in the cytosol, hormone receptor complex binds to HREs on DNA
Horome receptor elements
Specific DNA sequences where the hormone receptor complex can bind
Binding at HREs
Infleunces rate of transcription, with each steroid hormone affecting the gene expression of many different genes
Transcription Factors
Proteins that when bound to dna can either stimulate or inhibit transcription
(receptors for hydrophobic signalling molecules)
Examples of hydrophobic signalling molecules
The steroid hormones oestrogen and testerone