Hydrophilic Signals and control of transduction Flashcards
What can hydrophilic signalling molecules not do and what does this mean?
diffuse through cell membranes. This means that these molecules must bind to a receptor on the cell surface for anything to occur
What are the most common hydrophilic signalling molecule?
These types of signalling molecules are most commonly peptide hormones (insulin)
What happens as hydrophilic signalling molecules bind to receptors?
As they bind to receptors they cause a ligand conformation change
What is hydrophilic signal transduction?
The signal molecule does not enter the cell, but causes a cascade effect starting on the inner membrane side of the receptor protein, which will be transmembrane
What is the result of hydrophilic signal transduction?
This cascade will either be in the form of G-proteins or phosphorylation by kinase enzymes