HW Advance Trial Data

Question 0

Driveline Infections?

Answer 0

12.1 % (17pts) ..29ppy

Question 1

Stroke Rate?

Answer 1

¥ Ischemic 7.1% (10/140) .11ppy
£ Hemorrhagic 5.7% (8/140) .09ppy

¥ 6 events within 48hrs. 6 patients recovered. 1 died. 1 experienced hemorrhagic transformation 2 days after Ischemic Stroke. Counted in BOTH categories.

£ Incl. 2 events after exchange. 1 recovered, 1 died.

Question 2

Thrombus?

Answer 2

4.2% (6/140)

2.1 % (3/140) Confirmed .03ppy
2.1 % (3/140) Procedure related..03ppy
Defined as pump dysfunction within 72hrs. 2 resulted from nonstandard implant procedure With ingestion of tissue

Question 3

Bleeding?

Answer 3

GI Bleed 10.7% (15/140)

> 4U PRBCs within 7d 7.9% (11/140)

Req. Surgery 14.3 (20/140)

Question 4

Hemolysis?

Answer 4

3.6% (5/140) .06ppy

Question 5

Survival?

Answer 5

180d 94%

1year 91%