HUS Flashcards

1
Q

What is the classical triad of HUS?

A

Acute kidney injury
Microangiopathic haemolytic anaemia
Thrombocytopenia

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2
Q

What age is HUS seen in?

A

Young children

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3
Q

What is the cause of HUS?

A

Most cases are secondary (termed ‘typical HUS’):
Shiga toxin-producing Escherichia coli. This is the most common cause in children, accounting for over 90% of cases
Pneumococcal infection
HIV
Rare: systemic lupus erythematosus, drugs, cancer

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4
Q

How is HUS managed?

A

Supportive care- fluids and transfusion or dialysis if needed
No role for ABX

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