Hunger Hormones - Ghrelin and Leptin Flashcards

1
Q

Name the two main hormones in relation to hunger.

A

Ghrelin and Leptin.

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2
Q

Which is the only orexigenic gut hormone?

A

Ghrelin

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3
Q

Define orexigenic:

A

Appetite stimulating

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4
Q

What impact does being obese have on ghrelin levels?

A

Obese individuals have less ghrelin, this rises when dieting.

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5
Q

What impact does Ghrelin have on appetite?

A

Ghrelin is an appetite stimulant.

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6
Q

What impact does Leptin have on hunger?

A

Leptin suppresses hunger.

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7
Q

What is the difference between appetite and hunger?

A

Appetite is the desire to eat, whilst hunger is the drive to eat.

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8
Q

How does the rise in ghrelin when dieting make effective dieting harder for obese individuals?

A

Low tolerance to the hormone, will have a high appetite more quickly than non-obese individuals.

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9
Q

TRUE or FALSE, leptin and ghrelin both act on the hypothalamus

A

TRUE

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10
Q

Ghrelin acting on the hypothalamus stimulates the release of which appetite stimulant?

A

Neuropeptide Y

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11
Q

Leptin acting on the hypothalamus stimulates the release of which hunger suppressant?

A

Melanocyte stimulating hormone (MSH)

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12
Q

What happens to Ghrelin levels between meals?

A

Ghrelin levels rise when the stomach is empty.

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13
Q

Ghrelin only has an active form, TRUE or FALSE?

A

FALSE, Ghrelin has both an active and inactive form.

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14
Q

What occurs as a result of administering ghrelin, both peripherally and centrally?

A

Stimulates food intake.

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15
Q

Where is leptin produced?

A

White adipose tissue

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16
Q

What happens to leptin in obese individuals?

A

Leptin can become defective as obese individuals become resistant to the hormone.

17
Q

What factors drive appetite?

A

External and psychological factors.

18
Q

What factors drive hunger?

A

Central and peripheral internal factors.