Humoral vs. Cellular Immunity Flashcards
What are the two main types of immunity discussed?
Humoral immunity and cellular immunity
What type of cells produce antibodies?
B-Cells
What is the role of T-Cells in the immune system?
Part of cellular immunity and non-antibody producing
What are the effector cells produced by B-cells?
Plasma cells
What do plasma cells secrete?
Antibodies
What is the humoral arm of the immune system responsible for?
Producing antibodies to combat freely circulating pathogens
What activates B-cells?
Antigen binding to receptors followed by a co-stimulatory signal
What are the steps involved in humoral immunity?
- B-Cell binds to the antigen
- B-Cell differentiates into a plasma cell
- Plasma cells proliferate and produce antibodies
What is the role of helper T-cells?
Secrete cytokines that stimulate other cells
What type of pathogens do cytotoxic T-cells attack?
Virally infected cells and tumor cells
What is the primary function of cellular immunity?
Control of intracellular pathogens
What is the first step in the cellular immunity process?
T cell binds to an antigen complex on the surface of the infected cell
What role do macrophages play in cellular immunity?
They are activated during the immune response
What happens to T cells after they are activated?
They become cytotoxic and induce apoptosis of the target cell
Fill in the blank: The effector cells produced by T-cells include _______.
helper T-cells and cytotoxic T-cells
True or False: B-Cells are involved in cellular immunity.
False
In which organ are T-Cells produced?
Thymus
In which organ are B-Cells produced?
Bone marrow
