Humidity, Aerosal Therapy, Nebs, and Enclosures Flashcards
Heat Moisture Exchange principles
primary function of the upper respiratory tract is to heat, filter, and humidify gas. Nose is better at conditioning gas than mouth
Gas arriving in the lungs at body temp has what percentage of relative humidity?
100%
Definition of humidity
water vapor in a gaseous state; exerts a partial pressure
Partial pressure exerted by what is dependent on what?
temperature and relative humidity
BTPS conditions
temp: 37 C/98.6 F; 44mg/L absolute humidity; 47 mmHg (partial pressure); 100% relative humidity
Definition of saturation
the max amount of humidity a gas can carry at a given temp; also its capicity
If you allow a gas to cool you get what?
rainout or condensation
Warm gas has more what than a cold gas?
capacity
Absolute humidity definition
actual amount of water vapor in a gas, expressed as weight/unit volume
Relative humidity definition
a ratio or percentage of the actual water vapor content of a gas compared to the amount it could hold if it were saturated
RH equation
content/capacity X 100
Body Humidity definition
also called percent body humidity. It expresses how much water vapor is in inspired gas compared to BTPS air
Humidity deficit definition
the (absolute) different b/w alveolar water vapor content and the water vapor content of inspired air. It is the amount of water vapor that must be supplied by the mucosa
What is the purpose of a humidifier?
to condition inspired gas by inc. water vapor content. Thereby preventing drying of mucosa.
Room temperature humidifiers can be used when?
by patients with a normal upper airway. For example a nasal cannula >4LMP
What damage can dry gases cause?
mucosal damage, cellular damage, chronic inflammation, increased sputum viscosity
What are some signs and symptoms of inadequate airway humidification?
atelectasis, dry cough, inc.airway resistance, inc. WOB, inc.incidence of infection, substernal pain (chest pain), thick secretions
What are some type of patients that have special humidification needs?
infants/peds, asthmatics, upper airway inflammation, hypothermia, bypassed airway
What temperature of the gas can cause airway burns?
> 44 C
Factors affecting efficiency of a humidifier are what?
time (how long the water and gas are in contact with each other), surface area, temperature
Bubbler humidifier
unheated- use small bore oxygen supply tubing, 20-40% BH, low risk of bacterial infection, bubbles tend to cool water during use, more efficient at lower flows (<5LMP), Heated- use large bore corrugated tubing
Heated bubbler- high flow
one brand name is Cascade, up to 100 LMP, high efficiency, can provide 100% BH, temperature range 24-49 C (75-120 F)
Heated wick-high flow
wick absorbs water increasing surface area. acts like a home thermostat, Concha Therm II is the most common brand, heated wire circuit (optional), auto feed water, 100% BH, servo controlled temperature
Passover
heated, high flow, 100% BH, servo controlled temperature, examples Isolettes, Fisher&Paykel models, and Emerson mech. vents
HME
heat moisture exchangers (nose, artificial nose), exhaled heat and moisture retained in device, best suited for short term patients or daytime use on ventilator dependent patients, efficiency dependent on temperature and humidity of gas, flowrates, surface area of unit, and thermal conductivity of housing
Types of HME
Simple (paper, plastic, metal, 50% efficiency) Hygroscopic (paper, wool, foam+salts, 70% efficiency) Hydrophobic (paper, foam, slightly more than 70% efficiency)
Contraindications to HME
thick secretions, temperature less than 32 C, minute ventilation >10LPM, exhaled Vt less than 70% of inspiratory Vt
Vapor Phase humidification
Brand: Vapotherm, newer brand is Precision Flow, main use is high flow nasal cannula, also used for masks and trach collars,95-100% BH at 33-40 C
What cartridge and flows is acceptable for an adult?
High flow cartridge with flows 8-40 LPM
What cartridge and flows are acceptable for a peds patient?
High flow cartridge with flows 8-20 LPM
What cartridge and flows are acceptable for infants
Low flow cartridge with flows 1-8 LPM
Optiflow
high flow heated nasal cannula, flow rates up to 60LPM for adults
Capillary Force Vaporization
capillary action draws water into a heated disk. water is vaporized under pressure. Can be used with high flow cannula or for mech. vents
Most pneumatic nebs operate on what two principles?
Bernoulli and Venturi
SVN
small volume neb, usually holds 5-30mL, intermittent use(10-20 minutes with meds), output 1-2 mL/min, usual flowrates 6-8 LMP, particle size is inversely proportional to flowrate, inc. residual volume
LVN
large volume neb, used for few hours to days, most common for bland aerosol delivery, noisy with high flowrates and low FiO2, heated but not servo controlled
When would you need to use double nebs?
greater than 50%
What is an immersion heater
it goes directly into water, possible contamination if not cleaned ofter
Babbington or Hydrosphere
hollow sphere bathed in liquid, can entrain room air, used in oxygen tents, no longer produced
SPAG
small particle aerosol generator, designed to be used with Ribravirin, used for infection with RSV (viral), drying chamber, high cost of meds, takes 3 days for meds to work, use full isolation gear when unit is running
Centrifugal
AKA spinning disk, commonly used as room humidifer, best to use distilled water, produces mist, needs regular cleaning
Ultrasonic
frequency determines particle size, high output 6ml/min, very dense aerosol produced, commonly used for sputum inductions, med delivery, and room humidification, breaks easy, low residual volume