HUMAN PEDIGREE

Question 1

In a pedigree, a couple has three children: one unaffected, one affected, and one carrier. What is the most likely mode of inheritance?

Question 2

homozygous dominant and heterozygous trait

Answer 2

AUTOSOMAL DOMINANT

Question 3

Trait carried on a recessive allele must have a homozygous recessive genotype; two affected parents must have all affected children; two unaffected parents can have affected children, given that they are heterozygous

Answer 3

AUTOSOMAL RECESSIVE

Question 4

affected woman = homozygous dominant and heterozygous for the dominant allele; affected man = one X dominant allele; any affected father has all affected daughters; an affected mother can have unaffected children if heterozygous

Answer 4

x-linked dominant

with skipping generation

Question 5

an affected woman have to have both recessive alleles to have the disorder; unaffected woman if homozygous dominant or heterozygous x alleles; affected mothers have all affected sons; two affected parents will have all affected children

Answer 5

x-linked recessive

with skipping generation

Question 6

only men can be affected

Answer 6

y-linked