Human Growth, Developmentally disabled, Flashcards

1
Q

transference?

A

Transference: A set of expectations, beliefs, and emotional responses that a patient brings into the doctor patient relationship

CounterTransference: Physicians unconscious or unspoken expectations and feelings about a patient

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2
Q

categories of temperament

A
  • Temperament Patterns of arousal and emotionality that represent consistent and enduring characteristics in an individual
  • Temperament refers to how children behave, as opposed to what they do or why they do it.
  • not fixed/unchangeable

Easy babies: Babies who have a positive disposition; their body functions operate regularly, and they are adaptable

Difficult babies: Babies who have negative moods and are slow to adapt to new situations; when confronted with a new situation, they tend to withdraw

Slow-to-warm babies: Babies who are inactive, showing relatively calm reactions to their environment; their moods are generally negative, and they withdraw from new situations, adapting slowly

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3
Q

attachment

A
  • Attachment The positive emotional bond that develops between a child and a particular individual

When children experience attachment to a given person, they feel pleasure when they are with them and feel comforted by their presence at times of distress.

As children become more independent, they can progressively roam farther away from their secure base.

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4
Q

object permanence appears?

A
  • The understanding that objects continue to exist when out of sight
  • Usually partially complete by 8-12 months and established by 12-18 months
  • Incomplete at first: Children will only look for the item where it was last seen instead of using inference to find where it has been moved

Reactive Attachment Disorder of Infancy/Childhood:

  • child exposed to poor care/abuse
  • Inhibited Type - Child is withdrawn or unresponsive
  • Disinhibited Type - Child approaches and cuddles up to strangers
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5
Q

stranger anxiety?

A
  • caution and wariness displayed by infants when encountering an unfamiliar person (usually seen at 8-10 months)
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6
Q

separation anxiety appears?

A
  • Separation anxiety The distress displayed by infants when a customary care provider departs (usually first seen at 6-8 months and peaks at 14-18 months)
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7
Q

Eriksonian stages of psychosocial development?

A
  1. Trust vs. mistrust: birth-1 year
    - trust develops when environment responds to stimuli, mistrust when experiences frustration and deprivation: depends on how well their needs are met by caregivers
    - “hope”
    - failure of this first phase can cause psychosis, depression and addictions later in life.
  2. autonomy vs. shame and doubt: 1-3 years
    - develop independence and autonomy if they are allowed the freedom to explore, or shame and self-doubt if they are restricted and overprotected
    = “Will” phase
    - failure can cause paranoia, OCD and obsessive personality disorder
  3. initiative vs. guilt: 3-6 y/o
    - goal-directed behavior, initiative, conflict when independent actions cause negative results
    - “purpose”
    - failure = phobias
  4. industry vs. inferiority: 6-12 y/o
    - learning to take pride in accomplishments, or can cause sense of failure and inferiority d/t interactions w/ other adults
    - “competence”
  5. Identity vs. Identity confusion: 12-21 y/o
    - development of indepdent ego structure
    - “fidelity” = faithfulness to sense of self
    - failure = delinquency, gender identity disorders, psychosis
  6. Intimacy vs. Isolation: 21-40 y/o
    - must have solid sense of identity in order to form necessary relationships
    “Love”
    - failiure = schizoid personality, prejudice
  7. Generativity vs. stagnation: mid adulthood (40-60 y/o)
    - concern for future generations and society
    “care”
    - failure: substance abuse, marital infidelity, “mid-life crisis”
  8. Integrity vs. Despair: 60+
    - ability to accept one’s life as it had been and take responsibility for it
    - coming to terms w/ possibility of death
    “wisdom”
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8
Q

periods of cognitive theory of development

A
  • Four factors influencing cognitive behavior

Maturation of the nervous system

Experience

Social transmission of information

Equilibration (innate tendency for mental growth to progress toward increasingly complexity and stability)

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9
Q

Piaget’s stages of cognitive development

A
  1. Sensorimotor stage (birth to 2 years)
    - develop object permanence
    - react to environment
  2. Preoperational thought (2-6 y/o)- preschool
    - ability to use symbols and language
    - no deductive reasoning
    - egocentric thought
    - magical thinking (phenomenalistic causality)
    - semiotic function
    - centration (focusing on one obvious element of stimulus rather than considering all information)
  3. Concrete operations (6-11 y/o)
    - egocentric thought replaced by operational thought, able to reason, follow rules, have morals
    - conservation (recognize objects are same even if change shape)
    - reversibility (liquid to ice)
    - social speech
    - rigid interpretation of rules
  4. Formal operations (11- late adolescence)
    - ability to use deductive reasoning in abstract ways
    - probability, philosophy, religion, politics
    - higher mathematics
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10
Q

levels of intellectual disability

A

Mild IQ of 50 to 55-70

Moderate IQ of 35 to 40-50 to 55

Severe IQ of 20 to 25-35 to 40

Profound - Level below 20 to 25

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11
Q

down’s syndrome features

A

trisomy 21 - single palmar transverse crease, protruding tongue, flat facies, small ears, thick neck

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12
Q

fragile x syndrome

A

Xq27

Affects males more severely delayed cognitive abilities, behavior problems, hand flapping, large ears, elongated faces and enlarged testicles.

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13
Q

learning disorders

A

= Inability to achieve in a specific area of learning at a level consistent with the person’s overall IQ

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14
Q

asperger syndrome

A
  • Relatively good verbal language
  • Milder nonverbal language problems
  • Restricted range of interests and relationships
  • Often engage in repetitive routines
  • struggle w/ peer relationships
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15
Q

autistic spectrum disorder

A

Impaired social interactions
Impaired ability to communicate
AND, a restricted range of activities and interests

onset:
- first three years of life
- boys 4x more likely

etiology:
- brain dysfunction with abnormalities in brain structure (including the cerebellum and cerebral cortex – frontal and temporal lobes),
- abnormalities in neurotransmitters such as serotonin and dopamine
- highly heritable disorder

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16
Q

Rett’s syndrome

A

mainly in girls

Normal development to age 4 then…

  • decreased social, verbal and cognitive skills
  • Hand wringing
  • Ataxia
  • Decreased IQ
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17
Q

feeding disorders of infancy…

A
  • not related w/ GI or other medical/mental disorder
  • failure to eat and gain weight over at least 1 mos
  • onset before age 6
  • May appear apathetic
  • children develop to be smaller than peers

Parent-child interaction problems my contribute to or exacerbate the feeding problem

Factors may include:
Temperament
Intrauterine growth retardation
Preexisting developmental impairments

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18
Q

tourette’s disorder

A

= Involuntary Motor Movements & Vocal Tics (Dopamine in Caudate Nucleus)

  • Median age of onset is 6-7 years, but can be seen as early as 2 years
  • Seen more often in boys (3-5 X) than girls
  • Duration may be lifelong or may resolve with adulthood

tx: antipsychotics

differentiate from transient tic disorder…
- presence of single/multiple motor/vocal tics for NO LONGER than 12 mos

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19
Q

major vs. mild NCD?

A

major NCD = significant cognitive decline which testing confirms
** Deficits interfere w/ADLs (not independent)

mild NCD = Modest cognitive decline documented by knowledgeable reporter
** Deficits do not interfere w/ADLs (is independent)

Characteristics of Neurocognitive Disorders:

  • problems w/ planning, organizing, learning, language, social cognition
  • signs: aphasia, agnosia, apraxia
    • ** Progressive onset, steady course (dementia is stead, delerium comes on abruptly)
  • No clouding of consciousness
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20
Q

which drug to avoid to tx NCD?

A

In all dementias, avoid anticholinergic meds!!!

**Cholinergic neurons are lost through toxic damage or cell death –> decreased acetylcholine transmission

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21
Q

Alzheimer’s disease

A

Epidemiology:

  • Most common cause of dementia
  • Diffuse atrophy, enlarged ventricles
  • Risk factors: Down Syndrome (extra APP), female sex, hx head trauma, lower education level, ApoE alleles
  • Apolipoprotein E: ε4 allele increases risk, ApoE ε2 is protective

Pathology:

  • amyloid plaques: APP (amyloid precursor protein) cleaved improperly to amyloid β42 –> plaques (extracellular) –> cause cell death
  • neurofibrillary tangles: Mostly phosphorylated tau protein folds and accumulates (intracellular)
  • Both –> neuronal death directly and via inflammatory pathways

Behavioral disturbances common:
- psychosis, depression, agitation, sundowning (stay up all night, sleep all day)

Tx:

  • AChE inhibitors! (Donzepizil, galantamine, Rivastigmine) - will help slow down progression
  • memantine (protects against glutamate toxicity)
  • anitpsychotics: black box warning of stroke!
  • AVOID BENZOS - cause resp. depression, addiction, increased risk of falls
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22
Q

vascular NCD

A
  • Deficit onset relates to a cerebrovascular event & decline prominent in complex attention & frontal/executive fxn
  • More common in men
    • More abrupt onset, step-wise decline
  • Important to control risk factors (smoking, BP, glucose, aspirin, etc)
  • Can try acetylcholinesterase inhibitors
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23
Q

Frontotemporal NCD

A

“Bad guys”

Insidious onset/gradual progression w/2 variants:

  1. Behavioral (disinhibited, apathetic, dramatic personality changes, ritualized bx, hyperoral, decline in social/executive fxn, overreaction)
  2. Language (production, naming, grammar, etc)
  • MRI shows atrophy of frontal and temporal lobes
  • more common in men
  • earlier onset in 50s
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24
Q

NCD w/ Lewy Bodies

A

= AD + PD (visual hallucinations, tremor, dementia!)

Pathology: Lewy inclusion bodies (intraneuronal protein aggregates, mostly α-synuclein) –> cell death

Difficult to distinguish, overlap with other dementias especially PD

** Psychosis (esp visual hallucinations); parkinsonian features; occasional fluctuating mental function can mimic delirium and confound dx

tx: Paradoxical antipsychotic tx reaction (psychosis and ↑ side efx);
- consider acetylcholinesterase inhibitor

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25
NCD d/t Prion disease
Rapid onset/course Motor features of prion dz (clonus, ataxia, biomarker evidence) Triphasic waves on EEG for CJD
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HCD d/t Huntington's disease
AD, 50% inheritance - CAG trinucleotide repeat --> mutant protein --> neuronal death sx: - Abulia (lack of motivation), psychomotor slowing - Complex tasks first, memory/language later - Motor abnormalities (chorea) - Mood disturbances and/or psychosis is common Tx: antipsychotics, acetylcholinesterase inhibitors, mood stabilizers, SSRI
27
NCD d/t parkinson's disease
- α-synuclein or tau protein in substantia nigra; Lewy Body involvement common ** Distinguish from NCD w/Lewy Body by time frame (NCD PD requires cognitive decline ≥1 yr dx of PD) - think LBD if dementia happens quicker
28
psychosis
= disruption in the experience of reality (includes delusions and hallucinations) * this is a sx, never a ddx! partial ddx for psychosis: - SLE, acute intermittent porphyria, Major Depressive Disorder, Bipolar Disorder, seizures (esp TLE), Schizophrenia, Schizoaffective disorder, substance intoxication, Delirium, Dementia, adverse drug reaction, etc.
29
delusion
= misperception of existing stimuli - fixed, false belief not consistent w/cultural or religious background. Can be bizarre or non-bizarre (thought broadcasting, ideas of reference, grandiose, alien chips, erotomanic, persecutory, partner cheating, etc)
30
hallucination
= responding to stimuli that doesn't exist false sensory perception not associated with real external stimuli (auditory, visual, tactile, gustatory, olfactory) ** note: personality disorders don't have hallucinations (except for borderline)
31
schizophrenia
= NOT split personality - est. 1% of population, men=women - Typical onset: late teens to late 20s, men earlier than women - Wide range of various mental disturbances - Increased suicide risk; higher medical co-morbidities – some stats say up to 50% (15-20 year shortened life span...) - More likely to be victim of violence Typically have prodromal period: - “first break” can be mild to severe - often results in someone acting strange, messy, pulling away socially DSM V Criteria for DDx: * * ≥2 of the following, each present for a significant portion of a 1-month period- prodrome (or less if successfully treated): - delusions - hallucinations - disorganized speech (e.g., frequent derailment or incoherence) - grossly disorganized or catatonic behavior - negative symptoms - social/occupational dysfunction * * signs persist for at least 6 months, including 1 mos of above sx ** The following must be ruled out: Schizoaffective, Mood Disorders, substances, general medical conditions, autism spectrum Pathophysiology: - ?? not sure: could be inflammatory, infectious, often genetic, d/t marjuana * * see ventricular enlargement of 3rd and lateral ventricles - prefrontal cortex may be involved...
32
symptoms of schizophrenia
Positive symptoms: - Hallucinations and delusions: Hallucinatory content varies greatly and usually auditory (AH) (visual hallucinations not as common) - Disorganized speech/behavior Negative symptoms: - Lack of motivation - Affective blunting – often blunted to flat - Cognitive blunting - Impaired social functioning and social withdrawal
33
NTs of schizophrenia
1. “Dopamine hypothesis” – xs dopamine makes people psychotic! - supported by efficacy of antipsychotics 2. Seratonin hypothesis: - plays a role in negative sx! LSD causes psychosis 3. Glutamate hypothesis: - Hypo/hyperfunction at various receptors including NMDA
34
tx of schizphrenia
Major SE's of antipsychotic tx: - mvmt disorders (dystonia, akathisia, parkinsonism, tardive dyskinesia) - neuroepileptic malignant syndrome (NMS): – total dopamine blockade, causing rigidity of mm. and VERY high fever (must tx w/ dopamine agonist, and control psychotic behavior w/ Benzos) - anticholinergic SE's - sedation - weight gain * * Clozapine: BEST drug, but BAD SE’s - All of the above PLUS agranulocytosis (& others) --> restricted use - Can ↓ suicidality
35
schizophreniform disorder
"Schizo lite" - Similar to schizophrenia except symptom duration ** Symptoms of schizophrenia lasting >1 month but
36
schizoaffective disorder
Can be a difficult dx to make ** Features of both schizophrenia and depression or bipolar illness; Requires 2 weeks of schizophrenia symptoms in the absence of mood symptoms AND the presence of mood symptoms for a substantial part of the lifetime illness course Tx: psychosis with antipsychotics, mania with mood stabilizers, depression with antidepressants. Combine as necessary.
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brief psychotic disorder
Psychosis >1 day but
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Delusional Disorder
* * ≥1 month of a delusion (erotomanic, persecutory, grandiose, jealous, somatic) * *Does not meet basic schizophrenia criteria; behavior and function usu not affected Women > men, usu mid-late life R/O medical causes (eg, tumors, TLE, etc) Tx: psychotherapy; poor response to antipsychotics NOTE: - erotomanic = thinks a celebrity is in love with them - somatic = thinks something is growing out of body
39
bipolar disorder
= "a group of disorders in which a patient has sustained mood episodes in both directions (elevated or depressed)" - total BAD is more common in women, age of onset 25 y/o (men have earlier onset) ** Manic Episode ** = Presence of abnormally elevated, expansive, or irritable mood for at least one week : "bigger, faster, better" = + 3/7 characteristics -Inflated self esteem or grandiosity -Decreased need for sleep (more energy) -More talkative or pressured -Flight of ideas/subjective racing thoughts -Distractibility -Increased goal directed activity (more energy) -Excessive involvement in pleasurable activities Genetics: - parent gives 10-25% risk in pt. - family hx of MDD or BAD increases risk - concordance rate b/w twins is 70-90% differential ddx? - stimulants: amphet, PCP, cocaine, antidepressants - testosterone, hyperTH, pheo, FTD, schizo, ADHD, MDD
40
Bipolar type I
= a history of AT LEAST ONE MANIC EPISODE! - ANY manic episode = severe = BAD I - equal b/w genders - characterized by recurrent depressed and manic episodes w/ good functioning in between
41
Bipolar type II
= Hypomanic episodes and major depressive episodes. (more depressive episodes seen in general) - Symptoms do not meet full criteria for a manic episode - relatives of Bipolar II patients have higher rates of Bipolar II disorder than either Bipolar I or MDD ** Also has a higher rate of comorbidity with substance abuse disorders
42
Cyclothymic disorder
= “Chronic, fluctuating disturbance” between periods of hypomanic symptoms and periods of some depressive symptoms - Minimum course of 2yrs - Number of episodes not defined but “numerous” * * NO EPISODES OF MANIA, HYPOMANIA or MAJOR DEPRESSIVE EPISODES - 30% have family hx of BAD - 1/3 will progress to MDD or BAD - 2/3 respond well to Li
43
Mixed episode of BAD?
- Have Manic or Hypomanic episode with significant depressive symptoms simultaneously. - Mood and symptom picture alternates rapidly - Significantly elevated suicide risk - Likely to have more lifetime episodes
44
manic episode
= Presence of abnormally elevated, expansive, or irritable mood for AT LEAST ONE WEEK : "bigger, faster, better" NOTE: any psychosis = manic episode! = + 3/7 characteristics - Inflated self esteem or grandiosity - Decreased need for sleep (more energy) - More talkative or pressured - Flight of ideas/subjective racing thoughts - Distractibility - Increased goal directed activity (more energy) - Excessive involvement in pleasurable activities Mania course: - onset abrupt - lasts a week to months - briefer than depressive episode - significant risk of recurance - heightened risk of suicide in subsequent depressive episode
45
hypomanic episode
= Persistently elevated, expansive, or irritable mood, FOR AT LEAST 4 DAYS. - Accompanied by 3 or more manic symptoms but…. 1. Does not markedly impair social/occupational functioning. 2. No hospitalization needed 3. NO PSYCHOTIC FEATURES!
46
Bipolar treatment - moodstabilizers for mania? Maintenance stabilizers?
** Mood stabilizers ** Lithium Valproate Carbamazepine ** maintenance ** (or BADII) = Lamotrigine
47
Depressive Disorder
Prevalence: - 15% of people, 25% of women - 2/3 people don't know they have it, only 20% ddx get proper tx - rates of undetected depression in drug/alcohol users is at least 30% - 3rd most imp. disease burden in world! Epidemiology: - women>men - mean onset 40 y/o - not difft. b/w race or socioeceonomic Cause? - dysregulation of NE, serotonin and dopamine contribute - often see hypercortisol, abnormal thyroid regulation, blunted sleep d/t GH Genetics: 1st degree relatives 2-10x more likely! - 50% occurance in twins
48
Major Depressive Disorder (MDD): criteria? ddx?
Criteria: At least one of two: 1. depressed mood 2. anhedonia (lack of interest in pleasurable activities) >2 week period >4 symptoms: - decreased interest, - weight change, - sleep disturbance, - psychotmotor agitation, - loss of energy, - guilt, worthlessness, - poor concentration, - indecisiveness, - recurrent thoughts of death, suicidal NOTE: ALWAYS ASSESS FOR SUICIDAL IDEATION!!! differential ddx: - BAD, - dysthmia (long term depression) - cyclothymia (subthreshold chronic mood disorder w/ hypomanic moods) - schizo, anxiety disorder, personality disorder, seasonal affective disorder ** always assess for underlying medical condition: infection, endocrine, neuro disorder, neoplasm, vit deficiency
49
MDD course and prognosis ?
Course: - either chronic or relapsing - if untreated lasts for 6-13 mos (tx results in 8 weeks-3 month course) - often recurs Prognosis: prognosis if untreated: poor! - dysthmic disorder, alcohol abuse, anxiety, hospitalization,
50
dysthmia
= long term depression lasting at least two years!
51
cyclothymia
= dysthymia + hypomania (lasting at least 2 years) | chronic mood disorder w/ subthreshold depression w/ hypomanic moods mild bipolar, not quite hypomanic disorder!
52
treatment of MDD?
SAFETY IS NUMBER ONE!!! - always assess for suicidal thoughts and protect yourselves Suicide risk factors: male, elderly, caucasian, hx of attempts, co-morbid condition, drug/alcohol use, psychiatric illness, social isolation, low job satisfaction Treatment: 1 - Tricyclics (Nortriptyline, amitriptyline, impramine, desipramine): very effective but OD will result in DEATH, narrow TI **2 - SSRIs (Fluoxetine, Paroxetine, sertraline, citalopram) - safer, no risk of OD -- FIRST LINE TX! 3. MAOIs: tranylcypromine, phenelzine, Isocarbaxazid, selegiline (lots of problems, can cause HTN crisis w/ certain foods) **4. SNRI's (Venlafaxine, duloxetine) 5. Bupropion - also used for smoking, increased risk of seizures Dosing: - if don't respond, push AD up higher and make sure ddx is correct! - can combine but watch out for SSRIs and TCA together - can add lithium or thyroid to make them work better ``` SE's: GI Sexual Withdrawal “flu” (seen on w/drawal of SSRIs) Weight gain Seizure threshold HTN Sedation/Stimulation ``` ** ALWAYS INCLUDE PSYCHOTHERAPY IN TX AS WELL :)
53
Anxiety Disorder
Definition of Anxiety = - Excessive worry - Associated physical symptoms - Avoidant behavior - Unknown internal source vs. known external source - Sense of dread - Heightened apprehension ** Anxiety Disorders are the most common class of mental disorders present in the general population - Affecting 40 million adults in the US in a given year ** Sub-types of AD? - panic disorder, agorophobia, generalized anxiety, phobias, social anxiety, seperation anxiety, PTSD, OCD
54
Panic Disorder
= Recurrent, unexpected panic attacks - followed by at least on month of... - Persistent concern about having more attacks - Worry about the implications of the attacks - A significant change in behavior related to the attacks Panic Attack = A discrete period of intense fear or discomfort associated with multiple physical manifestations developing abruptly and reaching a peak within 10 min – ends quickly. **STARTS QUICK, ENDS QUICK** SX of panic attack: - Palpitations, Sweating, Tremor - Shortness of Breath, Chest pain and discomfort - Nausea, Dizziness - Fear of losing control, Fear of dying Prevalence: 2% of population, more common in females, onset early adulthood - attacks last a few minutes - associated w/ agoraphobia, depression and substance abuse - higher rate of suicide differential ddx: - CV disease, pulmonary disease, neuro disease, endocrine, drug intoxication, other mental disorder
55
Agoraphobia
(seen w/ panic disorders) = Anxiety about being in places or situations from which escape might be difficult or embarrassing or in which help may not be available in the event of having an unexpected panic attack
56
tx of panic disorders?
1. SSRI's - less SE, large TI (citalopram, fluoxetine, paroxetine, sertraline) 2. benzodiazepines - needed for rapid relief, given in beginning before SSRI's are able to work 3. Tricyclics 4. Venlafaxine Therapy! behavrioal therapy + Insight oriented psychodynamic psychotherapy
57
Phobias
= irrational fear resulting in a conscious avoidance of the feared object, activity or situation ** single most common mental disorders in the US: 10-25% of population are afflicted - increased risk of depression and substance abuse - specific phobias run in families, w/ first degree relatives often affected Types: 1. social phobia = Fear of humiliation or embarrassment in either general or specific social situations - commonly involving public speaking, urinating in public restrooms, stage fright Clinical Features: - panic attacks occur w/ severe anxiety when exposed to such phobia Tx: - exposure therapy, insight pyscotherapy specific phobia: benzo or SSRI social phobia: Beta blocker, SSRIm, benzo, buspirone
58
Obssessive Compulsive Disorder
- 2-3% of population, 4th most common disorder, men=women - 20 y/o age of onset - can occur in childhood Etiology: - dysregulation of seratonin - increased activity in frontal lobes, basal ganglia, and cingulum; treatment reverses this activity - Decreased size of caudates bilaterally Diagnosis: 1. Obsession: A recurrent and intrusive thought, feeling, idea, or sensation (increased anxiety) 2. Compulsion: A conscious, standardized, recurrent thought or behavior, such as counting, checking, or avoiding (decrease anxiety) * * if resist compulsion anxiety increases Examples: * Most common pattern compulsion: Obsession of contamination, compulsion of washing, avoiding * Next most common pattern: Doubt, followed by a compulsion of checking * Intrusive obsessional thoughts without a compulsion such as a sexual or aggressive act without * Need for symmetry or precision
59
Treatment of OCD?
``` Pharmacotherapy: Clomipramine SSRIs Lithium Benzodiazepines ``` Psychotherapy: Behavioral therapy (exposure, response and flooding) Family therapy
60
Post Traumatic Stress Disorder
Cause: - Experience an emotional stress of potentially life threatening magnitude that would be traumatic for almost anyone - Re-experiencing of the trauma through dreams and waking thoughts - Persistent avoidance of reminders of the trauma - hyperarousal - sx > 1 mos Epidemiology: 1-3 % of population (more in high risk groups) - Men usually combat related - Women usually related to assault Course: - Delay can be as short as a week to as long as 30 years - Symptoms fluctuate over time - Good prognosis predicted by a rapid onset of symptoms, short duration of symptoms, good premorbid functioning, strong support, absence of other psychiatric, medical, or substance disorder (very young and very old have harder time!) ``` treatment: SSRIs Mood stabilizers Hypnotics Anxiolytics Antipsychotics ```
61
Generalized Anxiety Disorder
= An excessive and pervasive worry accompanied by a variety of somatic symptoms, that cause significant impairment in social or occupational functioning or marked distress - person finds it difficult to control the anxiety epidemiology: - 3-8% - often co-exist w/ other psych disorders - more common women, often with other mental disorders - seek tx in 20's "i have been anxious for as long as i can remember" CF's: - Anxiety, motor tension, autonomic hyperactivity - Shakiness, restlessness, and headaches - Shortness of breath, excessive sweating, palpitations, GI symptoms - Easy startle, irritability - Usually seek out primary care physicians with somatic complaints - Chronic condition, usually life long Frequently co morbid depression, panic disorder, substance abuse ``` tx: Benzodiazepines Buspirone Mood stabilizers Antipsychotics SSRIs ```
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Blocking
- immature defense Temporarily or transiently inhibiting thinking. Affects and impulses may also be involved. Blocking closely resembles repression but differs in that tension arises when the impulse, affect, or thought is inhibited.
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Passive Aggressive behavior
- immature defense : Expressing aggression toward others indirectly through passivity, masochism, and turning against the self.
64
Regression
- immature defense Attempting to return to an earlier libidinal phase of functioning to avoid the tension and conflict evoked at the present level of development. It reflects the basic tendency to gain instinctual gratification at a less-developed period. "turning back maturational clock" ex. seen in children under stress such as illness (begins bedwetting again when hospitalized)
65
repression
- immature defense involuntarily holding an idea or feeling from consciousness (vs. suppression which is intentional withholding, mature response) ex. 20 y/o doesn't remember going to counseling during parents divorce
66
altruism
- mature defense alleviating negative feelings through unsolicited generosity (Using constructive and instinctually gratifying service to others to undergo a vicarious experience) i.e. mafia boss makes large donation to charity
67
humor
- mature defense Using comedy to overtly express feelings and thoughts without personal discomfort or immobilization and without producing an unpleasant effect on others. It allows the person to tolerate and yet focus on what is too terrible to be borne
68
suppression
- mature defense intentionally w/holding an idea or feeling from conscious awareness (vs. repression which is NOT intentional); temporary
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denial
- psychotic/immature defense Avoiding the awareness of some painful aspect of reality by negating sensory data. Although repression defends against affects and drive derivatives, denial abolishes external reality. Denial may be used in both normal and pathological states. i.e rxn in newly ddx AIDs pt. Clinical Example: A baby dies in a fire after the unsuccessful attempt by the mother to save the child. The mother later insists that the child has been saved by a neighbor. Normal in children In adults may be indicator of severe pathology such as psychosis ** often observed in clinical syndromes with patients w/ fatal illnesses or parents with severely ill children
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projection
- psychotic/immature defense Attributing one’s own personally unacceptable feelings to others Clinical Syndromes: Paranoid delusions and hallucinations. Normal in childhood: the imaginary playmate On a psychotic level, this defense mechanism takes the form of frank delusions about external reality (usually persecutory) and includes both perception of one's own feelings in another and subsequent acting on the perception (psychotic paranoid delusions). ex. a man who wants another woman thinks his wife is cheating on him
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acting out
- immature defense Avoiding painful feelings by behaving in an attention-getting socially inappropriate manner The unconscious fantasy is lived out impulsively in behavior, thereby gratifying the impulse, rather than the prohibition against it. Acting out involves chronically giving in to an impulse to avoid the tension that would result from the postponement of expression. ex: tantrums, A person may act out through substance use or sexual promiscuity
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Displacement
- immature defense transferring avoided ideas and feelings to a neutral person or object (ex. mother yells at child, b/c her husband yelled at her) Example: A man whose son was killed by a drunk driver attacks and seriously injures a drunken street person. clinically apparent in phobias
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Intellecualization
Excessively using intellectual processes to avoid affective expression or experience. Undue emphasis is focused on the inanimate in order to avoid intimacy with people, attention is paid to external reality to avoid the expression of inner feelings, and stress is excessively placed on irrelevant details to avoid perceiving the whole. Intellectualization is closely allied to rationalization. Clinical Example: A physician with a diagnosis of pancreatic cancer excessively discusses the statistics of the illness with his colleagues and family.
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Isolation of affect
- immature defense = separating feelings from ideas and events Example: A person who expresses no emotion when discussing the loss of a loved one – isolating her emotion from the sad event May occur in some obsessional states
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dissociation
- immature defense temporary, drastic change in personality, memory, consciousness or motor behavior to avoid emotional stress Separation of function of mental illnesses; mentally separating part of consciousness from reality; “forgetting "events have occurred Example: A woman sexually abused as a child has two distinct personalities in adulthood. Clinical manifestation: Dissociative Disorders
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reaction formation
- immature defense Transforming an unacceptable impulse into its opposite ex. person obsessed with sex enters a monastery Denying unacceptable feelings and adopting opposite attitudes Examples: Unconsciously behaving in a friendly fashion towards someone one does not like; the quiet, meek, “perfect” high school student who commits murder Clinical examples: obsessive compulsive disorders or personality Normal behavior in the three year old child
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sublimation
- mature defense replacing an unacceptable wish w/ a course of action that is similar to the wish but does not conflict w/ one's value system and is socially acceptable (vs. reaction formation which is doing the opposite) ex. teens aggression toward father redirected towards sports Clinical Example: A man whose son was killed by a drunk driver regularly speaks to high school students about the dangers of drunk driving
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anticipation
- mature defense Realistically anticipating or planning for future inner discomfort. The mechanism is goal-directed and implies careful planning or worrying and premature but realistic affective anticipation of dire and potentially dreadful outcomes
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splitting
- immature defense Believing people or events are either all bad or all good because of intolerance of ambiguity Example: A woman who believed that her physician was godlike – begins to think that he is a terrible physician when he is late for an appointment with her. Clinical example: Borderline Personality Disorder
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undoing
immature defense Adopting acts which symbolically cancel or reverse a previous unwanted act or thought or event. A woman who was an immaculate housekeeper develops a hand washing compulsion after her child develops pneumonia. Normal: knocking on wood, saying Gesundheit, “I’m sorry. Clinical: compulsive acts, obsessional thoughts
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BPD hallmark defense mechanisms?
Splitting, projection, acting out
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OCD hallmark mechanisms?
Undoing, magical thinking
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rationalization
- immature defense Offering rational explanations in an attempt to justify attitudes, beliefs, or behavior that may otherwise be unacceptable, to avoid self-blame ex. after being fired claiming the job wasn't good anyways
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OCD hallmark mechanisms?
Undoing, magical thinking
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somatic symptom disorder
= physical symptoms w/ no identifiable physical cause - both illness production and motivation are UNCONSCIOUS. ** patient is concerned about the symptom, this is the biggest thing that they dwell on - persistent thoughts and anxiety about the symptoms (vs. illness anxiety where they make leaps for drastic ddx w/ hardly any sx) * symptoms not intentionally produced, unconscious motivation for illness - more common in women - often have persistent thoughts about seriousness of illness along w/ high anxiety about health - persistence symptoms = at least 6 mos - Health concerns override all other concerns - not reassured for long, utilize lots of care - Preoccupation with symptoms starts early and often spans many years
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illness anxiety disorder
= Preoccupation with having serious disease (w/ very little sx present) = "hypochondriasis" ** sx not intentionally produced, no conscious motivation - there are hardly any somatic sx, just misinterpretation of normal body functions - tend to not be reassured - Excessive health related behaviors or avoidance - Duration 6 months or greater - prognosis fair, middle/older aged - lots of doctor shopping, and checking behavior
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conversion disorder
= loss of sensory or motor function (paralysis, blindness, mutism) often following an acute stressor ** symptom NOT intentionally produced (unconscious), no conscious gain - clinical findings not compatible w/ medical or neuro conditions - pt. is aware of but sometimes indifferent toward symptoms ex: there is a emotional precipitant – i.e. in auto wreck and at scene of two people dying he knew, he was driving and on being found he reports he can’t move his arms … there are often psychologic underpinnings Prevalence: - often monosymptomatic - highly prevalent in neuro wards - much more common in females and adolescents - good prognosis - Conforms to pt’s understanding of disease, not physiology Management: - utilize benzos in short term and focused therapy
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factitious disorder
= patient CONSCIOUSLY creates psychologic and/or physical sx in order to assume "sick role" and get medical attention for PRIMARY GAIN ** conscious sx production w/ unconscious motivation - primary gain: get psychologic benefit - secondary gain: get tangible benefits of being sick, such as vicodin Prevalence: - typically socially conforming young females - Higher socioeconomic class - Intelligent, educated, employed in medically related field - Usually associated with personality disorder ``` Common sx/diseases: Intestinal bleeding Hematuria Fever Diarrhea Hypoglycemia Cancer Non-epileptic seizures Iron deficiency anemia Renal stones ``` Management: - Confrontation by both primary physician/psychiatrist
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munchausen syndrome
= chronic factitious disorder w/ predominantly physical signs and sx - characterized by a history of multiple hospital admission and willingness to undergo invasive procedures triad of: - Fabrication of disease - Ever-shifting complaints - intense frequenting of different hospitals Prevalence: - Typically men of lower socioeconomic class - Socially maladjusted - Average age of 30 - POOR PROGNOSIS
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munchausen syndrome by proxy
illness in a child or elderly pt. caused or fabricated by the caregiver. motivation is to assume a sick role by proxy - this is a form of child/elder abuse
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Malingering
- intention production of illness guided by secondary gains (i.e. financial, avoiding military, avoiding criminal prosecution, obtaining controlled substances, obtaining shelter) * * CONSCIOUS SX w/ CONSCIOUS MOTIVATION majority are male, lack of cooperation, often w/ antisocial personality disorder
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Cluster A personality disorders
"weird" = odd or eccentric; inability to develop meaningful social relationship. NO PSYCHOSIS; often genetically associated w/ schizophrenia 1. Paranoid: Pervasive distrust and suspiciousness of others such that their motives are very often interpreted as malevolent 2. Schizoid: (distant) - voluntary social w/drawal, limited emotional expression, content with social isolation (vs. avoidant) - emotionally cold and detached 3. Schizotypal: (magical thinking) - eccentric appearance, odd beliefs or magical thinking, interpersonal awkwardness
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Cluster B personality disorders
"wild" = dramatic, emotional, erratic; genetic assoc. w/ mood disorders and substance abuse 1. Antisocial: (sociopath) disregard for and violation of rights of others, criminality, impulsivity, males>females; must be 18> y/o and have hx of conduct disorder before 15 y/o. * * considered conduct disorder if 2. Borderline: unstable mood and interpersonal relationships, impulsive, self-mutilation, boredom, more common in females, emptiness, splitting is defense mechanism - seen as borderline b/w schizo and depression * * filled w/ turmoil and intensity, roller coaster of mood swings 3. HIstrionic: excessive emotionality and excitability, attn seeking, sexually provocative, overly concerned w/ appearance, overly dramatic, don't seen how they appear to others 4. Narcissistic: grandiosity, sense of entitlement, they deserve the best and admiration
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Cluster C personality disorders
"worried" - anxious, fearful; genetic assoc. w/ anxiety disorder 1. avoidant: hypersensitive to rejection, socially inhibited, timid, feelings of inadequacy, desires relationships w/ others (vs. schizoid) 2. Obsessive-compulsive: preoccupation w/ order, perfectionism, control; ego-syntonic: behavior consistent w/ one's own beliefs and attitudes 3. Dependent: submissive and clings, need to be taken care of, low self confidence
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tx of EPS sx d/t antipsychotics?
lorazepam, benztropine, amantadine (NOT L dopa)
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tx of children using antipsychotics?
aripiprazole (no weight gain) or risperidone (has increased PRL AND EPS)
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tx of NMS d/t antipsychotics?
bromocriptine (dopa agonist) | diazepam/dantrolene (mm. relaxant)
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tx of tardive dyskinesia d/t antipsychotics?
switch to quietapine or clozapine!
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egoistic type suicide
1. Have excessive individuation, tend to be apathetic, can no longer find a basis for existence in life. 2. Tend to be skeptical, disillusioned and give a “matter of factness” to their distress these people have excessive ego, they are apathetic, skeptical, disillusioned, no religion, they are matter of fact
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altruistic type suicide
1. Insufficient individuation. Has much will or energy. 2. Has eastern-like thought process, mayattempt to achieve “nirvana”. 3. Common in soldiers, religious martyrs,Hara-Kiri, Kamikaze. Strong sense of duty. don't have much individuation - kill themselves for duty
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anomic type suicide
1. Literal meaning is “deregulation”. Has a lack of restraint, irritation, disgust, anger 2. Often violent, i.e. murder-suicide 3. Unregulated emotions lead to violent actions against life in general 4. May have abrupt social change: divorce, loss of job, economic crisis, death of mate. "impulsive, irratable, angry, violent"
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fatalistic type suicide
1. Excessive regulation. Too much against them to be able to cope. 2. Common in prisoners and slaves 3. May be seen in very young husbands,new fathers etc. who are inexperienced and become easily overwhelmed by life.
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how to assess suicide risk?
``` S = sex (male gender) A = age (older) D = depression P = previous attempt E = Ethanol (ETOH) abuse R = rational thinking loss S = social support lacking O = organized plan N = no spouse S = sickness ``` 0-2 Outpatient follow-up 3-4 Supervised outpatient follow-up 5-6 Consider hospitalization 7-10 Hospitalization