Human Genomes Flashcards

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1
Q

Viral DNA

A

Retroviruses have inserted
information

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2
Q

Protein Processing

A

The addition of sugars and lipids to create glycoproteins and lipoproteins

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3
Q

True of False? Most of Human Genome does not encode protein.

A

True

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4
Q

What is the percentage of human DNA that can encode protein?

A

Only 1.5%

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5
Q

What is the rest of are the Genome in a Human DNA?

A

Repeated sequences, promoters and other control sequences, introns, noncoding RNAs(ncRNA), and viral DNA.

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6
Q

Repeated sequences

A

Telomeres, centromeres,
transposons etc

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7
Q

Promoters and other
control sequences

A

Guide enzymes that
control replication,
transcription & translation

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8
Q

Noncoding RNAs
(ncRNA)

A

*rRNA, tRNA, others
* Transcribed from
pseudogenes, but are not
translated
Rest of genome includes:

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9
Q

What is a genotype?

A
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10
Q

Phenotype

A
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11
Q

Allele

A
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12
Q

Describe the purpose of a test cross

A
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13
Q

Explain how the law of segregation and the law of
independent assortment reflects the events of meiosis

A

The law of segregation reflects the movement of homologous chromosomes into separate cells during meiosis I. The law of independent assortment reflects that each homologous pair of chromosomes aligns independently of other chromosome pairs during metaphase I of meiosis.

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14
Q

Monohybrid Cross

A

Mendel speculated that gametes contained
particulate units or “elementen”

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15
Q

What are Gene?

A
  • Gametes containing “elementen”
  • Different versions of the same gene are called
    alleles
  • Differ in DNA sequence at one or more sites
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16
Q

Remember these terms

A

Alleles = dominant (T) or recessive (t) version of
a gene
* Genotype = The alleles present in an individual
* Homozygous TT or tt
* Heterozygous Tt
* Phenotype = The trait observed
* Ex: Tall or Short
* Wild Type = Most common phenotype
* Mutant phenotype = A product of a change in
the DNA

17
Q

What are Punnett squares?

A

Boxes that represents genes in gametes and how they combine to make offspring

18
Q

Law of Independent
Assortment

A
  • The inheritance of
    one does not
    influence the
    chance of inheriting
    the other
  • Applies to genes on
    different
    chromosomes
19
Q

Autosomal Inheritance

A
  • Located on the non-sex chromosomes
  • They may be inherited as dominant or recessive
    conditions
  • Recessive conditions more likely with consanguinity
20
Q

A phenotypic ratio of 3:1 in the offspring of a mating of two organisms heterozygous for a single trait is expected when:

A

The alleles segregate during meiosis.
Mendel first proposed that alleles segregate from one another during the formation of gametes

21
Q
A