Human form and function 3 Flashcards

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1
Q

What do the adrenal cortex hormones mediate?

A

Long term stress responses

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2
Q

What is the adrenal cortex hormone function ?

A

participate in homeostatic regulation of metabolism.

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3
Q

What is the function of the glucocorticoids?

A

Glucocorticoids have a main effect on glucose metabolism and promote glucose synthesis from non-carbohydrate sources such as protein and fat so that more glucose is available in the blood circulation for cellular energy production.

These hormones can promote breakdown
of skeletal muscle proteins for synthesis of glucose when the body requires more glucose.

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4
Q

what is the main glucocorticoid?

A

cortisol

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5
Q

Main mineralocorticoid of adrenal cortex by adrenal gland

A

aldosterone

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6
Q

Adrenaline medulla hormones

A

The hormones produced in the adrenal medulla are adrenaline (epinephrine) and noradrenaline
(norepinephrine) which could mediate ‘short term stress responses

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7
Q

Upon extensive sympathetic nervous stimulation, What is the function of adrenal medulla hormones?

A

Secretes these hormones which can potentiate the “fight
or flight response” by increasing the heart rate and blood pressure, diverting blood to essential
organs (i.e heart, brain, skeletal muscles) and increasing metabolic rate.

The hormones secreted
by adrenal medulla are mainly involved in increasing the availability of chemical energy for
immediate use.

These hormones promote glucose release into the circulating blood by increasing
the rate of glycogen breakdown (in liver and skeletal muscles) and fatty acids release (from fat
cells) for energy production within the body cells.

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8
Q

What are the features of islets of Langerhans of the pancreas?

A

Pancreases can be considered an endocrine gland as well as an exocrine gland. It is located behind the stomach in the curve of the duodenum.

The endocrine part of the pancreas is the islets of
Langerhans which are clusters of cells scattered throughout the pancreas.

These pancreatic islets mainly secrete two hormones, glucagon and insulin which control the blood glucose level by opposing actions.

Alpha cells of the pancreatic islets secrete glucagon which mainly promote the blood glucose level increase.

Beta cells of the pancreatic islets secrete insulin which promotes
lowering of blood glucose level.

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9
Q

What are the main target sites of the pancreatic hormones?

A

Liver and skeletal muscles are the main target sites of these
hormones

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10
Q

What is the female gonad location?

A

pelvic cavity

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11
Q

Where do the paired male gonads lie in?

A

Paired male gonads (testes) lie in
the scrotum.

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12
Q

What are the functions of the ovaries and the testis?

A

In addition to the reproduction, ovaries and testes have endocrine functions.

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13
Q

What does the ovarian follicle and corpus luteum produce?

A

Ovarian follicle produces the hormone estrogen. Corpus luteum (the structure formed from
the ovarian follicle after ovulation) produces progesterone.

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14
Q

What are the functions of LH and FSH?

A

These female sex hormones along
with FSH and LH from the anterior pituitary regulate menstrual cycle, maintain pregnancy and
prepare mammary glands for lactation. They also help establish and maintain feminine sexual
characteristics. The ovaries also produce the hormone inhibin that inhibits secretion of FSH from
anterior pituitary.

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15
Q

What are the locations and the functions of the male sex hormones?

A

The main hormone produced and secreted by the testes (interstitial cells) is the male sex hormone,
testosterone. Testosterone regulates production of sperm and stimulates the development and
maintenance of masculine secondary sex characteristics. In addition, the testes (Sertoli cells)
produce inhibin that inhibits secretion of FSH.

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16
Q

Example for negative feedback mechanism of glucose metabolism?

A

In the absence of stimulation, the blood level of hormone will
decrease. Some hormone levels in the blood can be directly controlled by the blood levels of
the stimulus (e.g. insulin or glucagon by blood glucose levels). For example high blood glucose
levels stimulate the release of insulin hormone (from the pancreas) to the circulating blood which
acts on specifi c target tissues to lower the blood glucose level. When glucose level in the blood
reaches normal range, blood glucose level can in turn directly control the secretion of insulin
levels from the pancreas and prevent further lowering of the glucose level in the blood.

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16
Q

Example for negative feedback mechanism?

A

In the absence of stimulation, the blood level of hormone will
decrease. Some hormone levels in the blood can be directly controlled by the blood levels of the stimulus (e.g. insulin or glucagon by blood glucose levels).

For example high blood glucose levels stimulate the release of insulin hormone (from the pancreas) to the circulating blood which acts on specific target tissues to lower the blood glucose level.

When glucose level in the blood reaches normal range, blood glucose level can in turn directly control the secretion of insulin
levels from the pancreas and prevent further lowering of the glucose level in the blood.

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17
Q

Give an example for positive feedback mechanism

A

Positive feedback mechanisms involving oxytocin
hormone operate in childbirth and breast milk ejection

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18
Q

How do the positive feedback mechanisms occur? (1 way)

A

During labour, contractions of uterus are stimulated by oxytocin hormone released by the posterior pituitary. These contractions force the baby’s head into the uterine cervix stimulating its stretch receptors.
In response to stimulation
of stretch receptors, sensory neurons are stimulated again triggering more oxytocin release from
the posterior pituitary enhancing contractions of the uterus. This process repeats until the baby is
born. Afterwards oxytocin secretion stops as the stimulus

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19
Q

Name another way of positive feedback mechanism

A

During suckling, sensory neurons send the nerve impulses to the
posterior pituitary triggering release of oxytocin hormone to the circulating blood. Then oxytocin
acts on the mammary glands and induces contractions of smooth muscles in the mammary
glands to release milk. Milk release increases the sensory stimulus forming a positive feedback
that amplifi es the stimulus. In response to the positive feedback, more oxytocin is released
enhancing milk ejection

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20
Q

Name heat loss mechanisms

A
  • dilation of blood vessels in the skin which causes fi lling of blood capillaries with warm
    blood and radiating heat from the skin surface
  • increase sweat secretion from the sweat glands which promotes heat dissipation through
    evaporative cooling
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21
Q

Name heat gain mechanims

A

constriction of blood vessels in the skin which divert the blood from the skin to deeper
tissues thereby reducing heat loss through the skin surface
- shivering: rapid repetitive contractions of skeletal muscles to generate heat
- contracting hair erector muscles to generate heat to some extent
- stimulating secretions of more thyroid hormones (e.g. thyroxin) and adrenalin into the
blood which increase the metabolic rate and cellular metabolism (especially oxidation of
fat in the liver) to produce more heat

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22
Q

When the blood glucose level rise up over the normal range?

A

High blood glucose levels exceeding the normal limits, stimulate the secretion of insulin hormone from beta cells of the islets of Langerhans into the circulating blood. Insulin acts on specific target tissues to promote lowering of the blood glucose level.

Insulin in the circulating blood stimulates transport of glucose into the body cells and use of glucose by body cells for ATP production
(glucose may be broken down into carbon dioxide and water), conversion of glucose to glycogen in liver and skeletal muscle cells for storage, and conversion of glucose to fatty acids and storage
of fat in adipose tissues.

When glucose level in the blood reaches normal range, blood glucose
level can in turn directly control the secretion of insulin levels from the pancreas through negative
feedback. This mechanism prevents further lowering of the glucose level in the blood beyond the
normal limits.

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23
Q

When the glucose levels are below the normal limits, what happens?

A

Low blood glucose levels below the normal limit, stimulate the secretion of glucagon from alpha cells of the islets of Langerhans into the circulating blood.

Glucagon acts on specific target tissues to promote increase of the blood glucose level.

Glucagon promotes the breakdown of glycogen in the liver and skeletal muscles and release of glucose into blood.

When glucose level in the blood reaches normal range, blood glucose level can in turn directly control the secretion of glucagon levels from the pancreas through negative feedback which prevents further increasing of the glucose level in the blood beyond the normal limits.

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24
Q

What happens when blood level increases beyond the normal limits?

A

Low blood glucose levels below the normal limit, stimulate the secretion of glucagon from alpha
cells of the islets of Langerhans into the circulating blood. Glucagon acts on specifi c target tissues
to promote increase of the blood glucose level. Glucagon promotes the breakdown of glycogen
in the liver and skeletal muscles and release of glucose into blood. When glucose level in the
blood reaches normal range, blood glucose level can in turn directly control the secretion of
glucagon levels from the pancreas through negative feedback which prevents further increasing
of the glucose level in the blood beyond the normal limits.

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25
Q

What are the ways by which the blood osmotic level is obtained?

A

controlling the amount of water and
controlling the amount of salt gained and lost by the body.

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25
Q

What are the ways by which the blood osmotic level is obtained?

A

controlling the amount of water and
controlling the amount of salt gained and lost by the body.

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26
Q

What happens when blood osmolarity is increased beyond the normal limits?

A

When blood osmolarity is increased beyond the physiological limits, it is sensed by the osmoreceptors in the hypothalamus which stimulates the posterior pituitary to release ADH to the blood circulation.

ADH acts on the kidney tubules and stimulates the reabsorption of water
through distal convoluted tubules of the nephrons and collecting ducts producing concentrated urine.

When blood osmolarity is decreased, ADH is not secreted, so water reabsorption through distal convoluted tubules of the nephrons and collecting ducts stop thereby producing diluted
urine.

In addition, low blood volume and low blood sodium ions stimulate the kidneys to produce angiotensin II which stimulates the adrenal cortex to secrete aldosterone hormone.

Aldosterone stimulates the reabsorption of sodium ions by the kidney tubules which is accompanied by the
water retention, thereby increasing blood volume and blood pressure. Hence, kidneys play a major
role in osmoregulation in the human body.

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27
Q

What is the role of liver in homeostasis?

A

Carbohydrate metabolism
Fat metabolism
Protein metabolism
Breakdown of erythrocytes and defense against microbial infections
Detoxification of drugs and toxicants:
Production of heat
Storage of nutrients
Inactivation of hormones
Secretion of bile

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28
Q

What are the ways of asexual reproduction?

A

Budding
Fragmentation and regeneration
Parthenogenesis

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29
Q

Explain what happens during budding

A

Budding is a form of asexual reproduction in which new individuals arise form outgrowths of the animal.

e.g. Hydra – A localized mass of mitotically dividing cells,
develops into a small Hydra, which can eventually detach from the parent.

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30
Q

What happens during fragmentation and regeneration?

A

This is a form of asexual reproduction which involves
breaking of the body or part of the body into several pieces, followed by the growth of a separate individual from each piece.

Each fragment develops into a complete animal by regrowth of lost body parts (regeneration). e.g. Certain annelid worms, numerous sponges,
cnidarians.

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31
Q

What takes place during parthenogenesis?

A

This is an unusual form of asexual reproduction in which an egg develops
into a complete individual without being fertilized. Among invertebrates, parthenogenesis
occurs in some animals such as bees, ants, aphids and wasps. The progeny can be haploid
or diploid. In honey bees – males (drones) are fertile haploid adults that develop through
parthenogenesis, whereas females including both sterile workers and the fertile queen, are
diploid adults that developed from fertilized eggs. Parthenogenesis has also been observed
very rarely among vertebrates (e.g. some lizards and fi sh).

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32
Q

Describe the nature of the female gamete during the sexual reproduction?

A

the egg,
is large and non-motile

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33
Q

Describe the nature of the male gamete during sexual reproduction?

A

the sperm, is generally much smaller and motile.

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34
Q

Describe about gamete formation during sexual reproduction

A

In animals, reproductive cells called gametes (sperms and eggs) are
the vehicles that transmit genes from one generation to the next. Each gamete is a haploid,
unicellular reproductive cell. Gametes in animals are formed by meiosis in special organs
called gonads.

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35
Q

What are bisexual organisms?

A

n a bisexual organism (Hermaphrodite),
one individual has both female and male reproductive structures and therefore is able
to produce both male and female gametes by the same individual. e.g. Earthworms

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36
Q

Explain about unisexual organisms

A

*In unisexual organisms (dioecious), one individual bears either male or female reproductive
structures.

*Therefore production of male or female gametes occurs in separate organisms.
e.g. Humans

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37
Q

What are the requirements for the external fertilization?

A

*occurs in aquatic environments.

*In species with external fertilization, the female releases eggs while the male releases sperm into the external environment and
fertilization occurs in the water.

A moist habitat is almost always required for external
fertilization both to prevent the gametes from drying out and to allow the sperm to swim toward the eggs. e.g. Many invertebrates, amphibians, most bony fish.

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38
Q

What are organisms that show internal fertilization?

A

insects, reptiles,
mammals.

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39
Q

Explain about the internal fertilization

A

Internal fertilization is an adaptation that enables sperm to reach an egg even when the environment is dry.

The male copulatory organ delivers sperm and the female
reproductive tract often has receptacles for storage and delivery of sperm to mature eggs.

Internal fertilization is typically associated with the production of fewer gametes than external fertilization but results in the survival of a higher fraction of zygotes.

Internal fertilization often provides greater protection to the embryos. Many animals show parental care.

Internally fertilized eggs of birds and other reptiles possess shells and
internal membranes that protect against water loss and physical damage. Some retain the
embryo for a portion of any development within the female reproductive tract.

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40
Q

What are the advantages of asexual reproduction?

A

Asexual reproduction allows rapid multiplication of individuals from single parents. Hence no time
or energy is needed to be spent in searching mates for the reproduction. In asexual reproduction,
there is no or very little genetic variation within a population as the produced off spring are
genetically identical to each other and to the single parent. Therefore, asexual reproduction would
be more advantageous in stable, favorable environments as it can propagate successful genotypes
specifi cally. However, any mutation in the parent cell, can cause harmful eff ects on the survival
ability of the off spring in changing environments. If there is a harmful mutation in the organisms,
environment changes could be deadly to all the individuals in the population.

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41
Q

Advantages of sexual reproduction

A

Unlike asexual reproduction, sexual reproduction results in the production of a unique off spring by
combining genetic materials from two parents. Meiotic recombination during sexual reproduction
helps produce varied genotypes. Unique gene combinations formed during sexual reproduction
would be advantageous as this can enhance reproductive success and survival of a species in
changing environments. Benefi cial gene combination arising through recombination may speed
up adaptation. During sexual reproduction, shuffl ing of genes might allow a population to clear
sets of harmful genes more readily which would enhance the survival of the species.

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42
Q

What are the functions of the reproductive organs of the reproductive system?

A

gonads (testes) which produce sperm
and reproductive hormones,

epididymis which store mature sperms, accessory glands that secrete
products required for sperm movement

ducts that transport the mature sperm and glandular
secretions

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43
Q

What are the external male reproductive organs?

A

The external reproductive organs of a male are the scrotum and penis.

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44
Q

Function of the sertoli cells?

A

These cells secrete the hormone inhibin and nourish and provide attachment
for cells that are in different stages of spermatogenesis

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45
Q

What is the function of the leydig cells?

A

secrete the hormone testosterone and other androgens after puberty which
promote spermatogenesis in the tubules

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46
Q

What is the function of the epididymis?

A

Matured sperms are stored within the epididymis
until ejaculation.

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47
Q

What does the urethra run through?

A

The urethra runs through the penis
and opens to the outside at the tip of the penis which contains erectile tissues derived from
modifi ed veins and capillaries.

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48
Q

What is the function of the ejaculatory duct?

A

The ejaculatory ducts open into the urethra which is the passageway for both urinary excretion and delivery of sperms in semen into the female reproductive tract

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49
Q

Explain the basic process of spermatogenesis?

A

formation of spermatocytes
from a spermatogonium, meiotic division of the spermatocytes, and transformation of the four
resulting spermatids (from each spermatocyte) into spermatozoa (sperm)

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50
Q

Explain about the sperm

A

Each sperm is made up of three main parts, the head, midpiece (body) and tail.
Head of the sperm contains the haploid nucleus carrying the paternal genetic material. A special
vesicle called the acrosome is present at the anterior end of the head. It contains hydrolytic
enzymes such as trypsin and hyaluronidase that help the sperm to penetrate the outer layers of the
ovum. Midpiece of the sperm contains many mitochondria that provides ATP necessary for the
movement of the tail.
The tail of the sperm contains a long fl agellum with typical 9+2 arrangement of microtubules. It is
produced by the centriole found near the base of the nucleus. The tail enables the sperm to swim
along the female reproductive tract towards an ovum.

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51
Q

What does the semen contain?

A

Main fraction of
the semen is made up of secretions from seminal vesicles and the prostate gland.
The semen contains several components such as mucus, enzymes, prostaglandins, ascorbic acid,
citrate and fructose which promote the survival of sperm.

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51
Q

What does the semen contain?

A

Main fraction of the semen is made up of secretions from seminal vesicles and the prostate gland.

The semen contains several components such as mucus, enzymes, prostaglandins, ascorbic acid, citrate and fructose which promote the survival of sperm.

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52
Q

What is the function of the semen?

A

The semen provides a liquid medium for the sperm movement and also helps to neutralize the acidity in the female reproductive tract.

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53
Q

What kind of fluid does the seminal vesicle produce?

A

They are a pair of two small pouches that produce a thick, yellowish
fluid that is expelled during ejaculation

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54
Q

What is the function of the seminal fluid?

A

Seminal fluid is alkaline to protect the sperm in the acidic environment of the vagina.

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55
Q

What does the seminal fluid contain?

A

mucus, fructose (that provides most of the sperm’s energy), a coagulating enzyme (helps semen coagulates after ejaculation), ascorbic acid and local regulators called prostaglandins.

This fluid contributes to about 60% of the volume of semen.

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56
Q

What does the each seminal vesicle open into?

A

Each seminal vesicle opens into a short duct that joins the corresponding
vas deference to form an ejaculatory duct.

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57
Q

Where can the prostate gland be found in?

A

This gland is found below the urinary bladder

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58
Q

What does the prostate gland secrete?

A

It secretes a thin, milky fluid directly into the urethra through small ducts

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59
Q

What does the prostate gland secretions contain?

A

This milky secretion contains coagulants,
anticoagulant enzymes and citrate which is a sperm nutrient. This fluid contributes to about
30% of the volume of semen.

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60
Q

What does the pair of bulbourethral gland contain?

A

They are a pair of small glands found along the urethra below the
prostate.

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61
Q

What does the bulbourethral gland secrete?

A

These glands secrete a clear alkaline mucus that is able to neutralize any acidic
urine remaining in the urethra and lubricates the lining of the urethra.

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62
Q

Describe the hormonal control of the human male reproductive system.

A

· In males, in response to the release of GnRH from the hypothalamus (just before puberty),
results in the release of FSH and LH by the anterior pituitary. Rising levels of the FSH and
LH hormones at puberty promotes mature functioning of the male reproductive organs.
The hormones regulate the development, growth, pubertal maturation and reproductive
processes of the body.
· FSH and LH hormones direct spermatogenesis by acting on different types of cells in the
testis.
· FSH stimulates Sertoli cells to nourish the developing sperm.
· LH causes Leydig cells to produce testosterone and other androgens to promote
spermatogenesis.
· Two negative-feedback mechanisms control sex hormone production in males.
· Testosterone inhibits GnRH, FSH and LH in blood through its eff ect on the hypothalamus
and anterior pituitary.
· Additionally inhibin produced by Sertoli cells, acts on anterior pituitary gland to reduce
FSH secretion.
· These negative-feedback circuits maintain testosterone and other androgen levels in the
normal range.

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63
Q

What are the female gonads?

A

ovaries

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64
Q

What are the steps of human development?

A

Fertilization/conception and the formation of a human zygote
Cleavage of the zygote, blastocyst formation and implantation
Embryonic members / fetal membranes
Placenta and umbilical cord

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65
Q

Describe the steps up to puberty of oogenesis?

A

· Oogenesis begins in the female embryo with the mitotic division of primordial germ cells
that give rise to oogonia.
· Then oogonia divide by mitosis to form cells that begin meiosis, but stops at prophase I
before birth.
· Each of these developmentally arrested cell is called a primary oocyte. Each primary oocyte
is found within a small follicle, a cavity lined with protective cells. At birth, the ovaries
together contain about 1-2 million primary oocytes. Out of these about 500 fully mature
between the puberty and the menopause.

66
Q

What happens at the beginning of the puberty of females during oogenesis process?

A

· Beginning at puberty, follicle stimulating hormone (FSH) periodically stimulates a small
group of follicles to resume growth and development. Out of these only one follicle fully
matures each month. During this time the primary oocyte within the follicle completes
meiosis I and produces a secondary oocyte and the fi rst polar body. Then the meiosis II
starts, but stops at the metaphase.
· The secondary oocyte arrested in meiosis II is released at ovulation (with the fi rst polar
body), when its follicle breaks open.
· If a sperm penetrates the secondary oocyte, meiosis II completes and the secondary oocyte
divides into the mature ovum and a second polar body. Both meiotic divisions involve
unequal cytokinesis, with the smaller cells becoming polar bodies which will degenerate
eventually. If a sperm penetrates, there is a single mature egg (ovum) containing a sperm
head at the end of oogenesis. The fusion of the haploid nuclei of the sperm and the ovum
is called fertilization.

67
Q

What takes place after the process of ovulation?

A

· The ruptured follicle left behind after ovulation develops into the corpus luteum. Corpus
luteum secretes estradiol and progesterone hormones which help to maintain the uterine
lining during pregnancy.
· If the egg is not fertilized, the corpus luteum degenerates and leaves a small ,permanent
scar of fi brous tissue called corpus albicans on the ovary surface.
· A new follicle matures during the next cycle.

68
Q

Briefly mention the facts of Hormonal control of the human female reproductive cycles?

A

Although males produce sperms continuously, females
produce ova in cycles. There are two linked reproductive
cycles in a human female during their reproductive years;
the ovarian cycle and the uterine cycle (or the menstrual
cycle). The uterine cycle consists of changes that occur
about once a month in the uterus and these cyclic changes
in the uterus are controlled by the ovarian cycle, which
is cyclic events that occur in the ovaries. Both of these
cycles are regulated by hormonal activities which link
the two cycles, synchronizing ovarian follicle growth and
ovulation with the establishment of a uterine lining which
supports the development of embryo.

68
Q

Briefly mention the facts of Hormonal control of the human female reproductive cycles?

A

Although males produce sperms continuously, females
produce ova in cycles. There are two linked reproductive
cycles in a human female during their reproductive years;
the ovarian cycle and the uterine cycle (or the menstrual
cycle). The uterine cycle consists of changes that occur
about once a month in the uterus and these cyclic changes
in the uterus are controlled by the ovarian cycle, which
is cyclic events that occur in the ovaries. Both of these
cycles are regulated by hormonal activities which link
the two cycles, synchronizing ovarian follicle growth and
ovulation with the establishment of a uterine lining which
supports the development of embryo.

69
Q

What happens during menopause?

A

During this time the ovarian supply of oocytes runs out and
the estrogen production by the ovary decreases.

Ovaries become less responsive to the hormones
FSH and LH produced by the anterior pituitary.

70
Q

What happens during human development?

A

Fertilization/conception and the formation of a human zygote
Cleavage of the zygote, blastocyst formation and implantation

71
Q

Where is the glycoprotein in the oocyte?

A

the glycoprotein layer present between the oocyte’s plasma membrane and the surrounding cells.

72
Q

Where does fertilization occurs?

A

Fertilization takes place in the upper reaches of the oviduct within 12 to 24 hours after ovulation.

73
Q

How does the morula get nutrition?

A

endometrial secretion

74
Q

What are the distinct layers of the blastocyst?

A

Inner cell mass
trophoblast

75
Q

How does the trophoblast invade the endometrium?

A

The trophoblast grows outward and invades the
endometrium.

This is initiated by the enzyme secreted by the trophoblast to breakdown the uterine lining.

Then the trophoblast extends finger like projections into the endometrium.

76
Q

What does the trophoblast secrete?

A

Trophoblast begins to secrete human chorionic gonadotropin (hCG) hormone which has the action similar to LH.

The hormone hCG rescues the corpus luteum from degeneration
and sustains its secretion of progesterone and estrogen which maintain the uterine lining
preventing menstruation.

77
Q

What happens after the end of gastrulation stage?

A

After implantation, three germ layers are formed in the developing embryo at the end of the gastrulation stage.

Extra-embryonic membranes begin to appear which surround the
embryo.

The placenta is formed by the cells of trophoblast and the adjacent endometrial
tissues.

78
Q

Chorion functions?

A

the main embryonic portion of the placenta which is the structure for
exchange of materials between the fetus and mother.

It also protects the embryo/fetus
from immune responses of the mother.

Chorion produces hCG, an important hormone of
pregnancy

78
Q

Chorion functions?

A

the main embryonic portion of the placenta which is the structure for
exchange of materials between the fetus and mother.

It also protects the embryo/fetus
from immune responses of the mother.

Chorion produces hCG, an important hormone of
pregnancy

79
Q

Amnion functions?

A

protective membrane surrounding the embryo/fetus creating a fluid filled cavity which serves as a shock absorber and helps prevent desiccation.

80
Q

Yolk sac functions

A

Yolk sac contributes to the cells that will become blood cells until the fetal liver takes over.

It also is the source of primordial germ cells that migrate to the developing gonads.

81
Q

Allantois functions?

A

small outer-pouching of the yolk sac that serves as an early site for blood
formation and is associated with the development of the urinary bladder.

82
Q

What does the placenta contain?

A

embryonic/fetal portion formed by chorionic villi of the chorion
and maternal portion formed by the endometrium

82
Q

What does the placenta contain?

A

embryonic/fetal portion formed by chorionic villi of the chorion
and maternal portion formed by the endometrium

83
Q

What does the placenta supply?

A

The placenta mediates the exchange of
material (nutrients, respiratory gases, metabolic wastes) between the embryonic/fetal and the mother’s circulatory systems.

The placenta supplies oxygen and nutrients to the fetus
from the maternal blood stream and excrete waste products from the fetus to the maternal blood stream.

The placenta also helps to provide immune protection to the developing embryo/fetus.

The placenta produces hormones (e.g. hCG, progesterone etc.) needed to
sustain the pregnancy.

83
Q

What does the placenta supply?

A

The placenta mediates the exchange of
material (nutrients, respiratory gases, metabolic wastes) between the embryonic/fetal and the mother’s circulatory systems.

The placenta supplies oxygen and nutrients to the fetus
from the maternal blood stream and excrete waste products from the fetus to the maternal blood stream.

The placenta also helps to provide immune protection to the developing embryo/fetus.

The placenta produces hormones (e.g. hCG, progesterone etc.) needed to
sustain the pregnancy.

84
Q

Movement of blood through placenta?

A

Oxygen poor blood from the embryo/fetus
travels to the placenta through the two arteries of the umbilical cord and passes through
fingerlike projections (chorionic villi) of the placenta where oxygen and nutrients are
acquired. Fetal blood (oxygen rich blood) leaves the placenta through the umbilical vein
leading back to the embryo/fetus.

85
Q

What happens during the first trimester?

A

the implanted embryo secretes hormones to regulate the mother’s
reproductive system and to indicate its presence.

The hCG hormone secreted by the embryo, maintains the corpus luteum in the ovary to secrete progesterone and estrogen. Some amount of this hCG passes from the maternal blood to the urine.

The presence of hCG in pregnant mother’s blood and urine can be easily detected and therefore is used as an early pregnancy detection test.

High levels of progesterone brings about rapid changes in the mother. Both ovulation and menstrual cycles stop, the maternal side of the placenta grows, and the breasts and the uterus get
larger.

Mucus in the cervix of the mother forms a plug which prevents the fetus from infections.

Most mothers experience nausea (morning sickness) during the first trimester.

86
Q

What happens during the second trimester?

A

By the second trimester, the level of hCG declines and as a result the corpus luteum deteriorates.

But the placenta takes over the production of progesterone and estrogens which helps to maintain the pregnancy.

Mother can feel fetal movements. As the fetus grows, mother’s abdominal organs become compressed and displaced.

87
Q

What happens during third trimester?

A

digestive blockage and frequent urination.

88
Q

What happens during fetal first trimester?

A

The first trimester is the most critical stage of development during which the rudiments of all major organ systems appear.

This is the main period of organogenesis (the development
of the body organs). The heart begins to beat by the 4th week (can be detected at 8-10 weeks).

By the 8th week, embryo is said to be the fetus as all the parts of an adult are present in rudimentary form. At the end of the 1st trimester, the fetus is well differentiated and about
5 -7 cm long.

89
Q

fetal second trimester?

A

By the end of second trimester, the fetus assumes distinctively human features. Organ
systems are completely developed in this stage. During the second trimester, the fetus grows
to about 30 cm in length and is very active so that the mother may feel the fetal movements.

90
Q

fetal third trimester?

A

The third trimester represents a period of rapid fetal growth. During the early stage of this
period, most of the organ systems become fully functional. During the third trimester, the
fetus grows to about 50 cm in length and weighs about 3-4 kg. Fetal activity decrease as it
fi lls the space within the uterus.

91
Q

Explain about maternal and fetal environmental tolerances?

A

During pregnancy the overall regulation of the mother’s immune system changes.

These changes allow the mother to keep the embryo in her uterus without rejecting as a foreign body even though half the embryo’s genes are inherited from the father and many chemical markers on the surface
of the embryo are foreign to the mother.

92
Q

What happens when the labor begins?

A

When labor begins, local regulators (prostaglandins)
and hormones (mainly estradiol and oxytocin) induce and regulate further contractions of the uterus.

This is a positive feedback mechanism as uterine contractions stimulate secretion of oxytocin which stimulates further contractions of the uterus.

92
Q

What happens when the labor begins?

A

When labor begins, local regulators (prostaglandins)
and hormones (mainly estradiol and oxytocin) induce and regulate further contractions of the uterus.

This is a positive feedback mechanism as uterine contractions stimulate secretion of oxytocin which stimulates further contractions of the uterus.

93
Q

What are the three stages of labour?

A

thinning and opening up (dilation)
of the cervix.

The second stage is the delivery of the baby.

In this stage, continuous and strong
contractions force the fetus out of the uterus and expell through the vagina. Delivery of the
placenta is the final stage of labor.

94
Q

Main hormone in milk synthesis and secretion?

A

prolactin hormone

95
Q

What kind of regulation does lactation have?

A

nervous and hormonal regulation

96
Q

The main hormone in promoting milk synthesis and secretion

A

Prolactin

97
Q

What happens in response to suckling?

A

In response to suckling by the new born baby (which initiates nerve impulses from touch receptors in the nipples) and decrease in estradiol and progesterone levels in the mother’s blood after
birth

The hypothalamus send impulses to the anterior pituitary to secrete prolactin hormone which stimulates the mammary glands to produce milk.

98
Q

What does suckling also stimulate?

A

Suckling also stimulates the secretion of
oxytocin hormone from the posterior pituitary gland and triggers the release (ejection) of milk
from the mammary glands.

This is a positive feedback mechanism as milk availability encourages
continuous suckling, so touch sensation on the nipple and oxytocin release continue further
ejecting milk from the mammary glands.

99
Q

What does colostrum contain?

A

sterile solution that contain nutrients such as
lactose, fatty acids, amino acids, minerals, vitamins, and water that are ideal for baby’s digestion,

100
Q

Why is human milk important?

A

baby’s digestion, brain development and growth

101
Q

What does human milk have?

A

Human milk includes proteins such as casein, lactalbumin and
immunoglobulins.

102
Q

Similarities of colostrum and true milk?

A

Colostrum and true milk provide nutrients for the baby and contain important antibodies that protect the infant. Several types of white blood cells are also present in the breast milk which
help the baby to resist microbial infections.

103
Q

Difference between colostrum and true milk?

A

Compared to the true milk, colostrum contains less
nutrients (less lactose and no fat) but they are adequate for the early nutritional needs.

104
Q

Difference between colostrum and true milk?

A

Compared to the true milk, colostrum contains less
nutrients (less lactose and no fat) but they are adequate for the early nutritional needs.

105
Q

Breast feeding advantages?

A

Breast feeding supports optimal infant growth, enhances intellectual development and fosters
mother-infant relations by establishing early and prolonged contact between them

106
Q

What are the deficiency symptoms of Vitamin A (retinol)?

A

Blindness, skin disorders, immunity
impairment

107
Q

What are the main dietary sources of Vitamin A (retinol)?

A

Dark green vegetables,
orange vegetables and fruits,
dairy products

108
Q

Give another name for vitamin A

A

retinol

109
Q

What are the deficiency symptoms of Vitamin D?

A

Bone deformities(rickets) in children,
bone softening in adults

110
Q

What are the dietary sources of Vitamin D?

A

Egg yolk, dairy products

111
Q

What are the dietary sources of Vitamin E?

A

Vegetable oils, nuts, seeds

112
Q

What are the deficiency symptoms of Vitamin E?

A

Nervous system degeneration

113
Q

What are the dietary sources of Vitamin K?

A

Green vegetables, tea,
produced by colon bacteria

114
Q

What are the deficiency symptoms of Vitamin K?

A

Defective blood clotting

115
Q

What are fat soluble vitamins?

A

Vitamins A,D,K,E

116
Q

Give another name for Vitamin B1

A

Thiamine

117
Q

What are the dietary sources of Vitamin B1?

A

Legumes, peanuts, whole
grains, pork

118
Q

What are the deficiency symptoms of Vitamin B1?

A

Beriberi(characterized by tingling,
poor coordination, susceptibility to
infection, reduced heart function)

119
Q

What are the dietary sources of Vitamin B2?

A

Dairy products, meats,
vegetables, enriched grains

120
Q

What are the deficiency symptoms of Vitamin B2?

A

Skin lesions (cracks at corners of
mouth)

121
Q

Give another name for Riboflavin

A

vitamin B2

122
Q

What are the deficiency symptoms of Vitamin B3?

A

Pellagra(characterized by lesions in
skin, mental confusion and diarrhea)

123
Q

What are the dietary sources of Vitamin B3?

A

Grains, nuts, meats

124
Q

Give another name for Vitamin B3

A

Niacin

125
Q

What are the deficiency symptoms of Vitamin B5?

A

Fatigue, numbness, tingling of hands
and feet

126
Q

What are the dietary sources of Vitamin B5?

A

Dairy products, fruits,
vegetables, grains

127
Q

Give another name for Vitamin B5

A

Pantothenic acid

128
Q

Give another name for Vitamin B6

A

Pyridoxine

129
Q

What are the dietary sources of Vitamin B6?

A

Whole grains, Meats,
vegetables

130
Q

What are the deficiency symptoms of Vitamin B6?

A

Irritability, anemia

131
Q

What are the dietary sources of Vitamin B7?

A

Meats, legumes, vegetables

132
Q

Give another name for Vitamin B7

A

Biotin

133
Q

What are the deficiency symptoms of Vitamin B7?

A

Neuro- muscular disorders, scaly skin
infl ammation

134
Q

What are the dietary sources of Vitamin B9?

A

Green vegetables, whole
grains

135
Q

What are the deficiency symptoms of Vitamin B9?

A

Anemia, birth defects

136
Q

Give another name for Vitamin B9

A

Folic Acid

137
Q

What are the deficiency symptoms of Vitamin B12?

A

Loss of balance, numbness, anemia

138
Q

What are the dietary sources of Vitamin B12?

A

Dairy products, eggs, meats

139
Q

Give another name for Vitamin B12

A

Cobalamin

140
Q

What are the dietary sources of Vitamin C?

A

Citrus fruits, broccoli,
tomatoes

141
Q

What are the deficiency symptoms of Vitamin C?

A

Scurvy (characterized by degeneration
of skin and teeth) , delayed wound
healing

142
Q

Give another name for Vitamin C

A

Ascorbic Acid

143
Q

What are the dietary sources of Calcium

A

Dairy products, dark green
vegetables, legumes

144
Q

What are the deficiency symptoms of Calcium

A

Loss of bone mass, impaired growth

145
Q

What are the dietary sources of Fe

A

Whole grains, green leafy
vegetables, legumes, meats,
eggs

146
Q

What are the deficiency symptoms of Fe

A

Anemia, weakness, impaired
immunity

147
Q

What are the dietary sources of P

A

Rice, bread, milk, dairy
products, fi sh, red meat

148
Q

What are the deficiency symptoms of P

A

Decaying of teeth and bones,
weakness

149
Q

What are the deficiency symptoms of K?

A

Muscle weakness, nausea , paralysis,
heart failure

150
Q

What are the dietary sources of K?

A

Fruits, vegetables, meat ,
dairy products, grains

151
Q

What are the dietary sources of I?

A

Sea foods , vegetables,
iodized salt

152
Q

What are the deficiency symptoms of I?

A

Goiter( enlarged thyroid glands)

153
Q

What are the dietary sources of S?

A

Foods containing proteins

154
Q

What are the deficiency symptoms of S?

A

Fatigue, Impaired growth, swelling

155
Q

What are the dietary sources of Na and Cl?

A

Table salt

156
Q

What are the deficiency symptoms of Na and Cl?

A

Reduced appetite, muscle cramps

157
Q

What are the dietary sources of Mg?

A

Green leafy vegetables,
grains

158
Q

What are the deficiency symptoms of Mg?

A

Disturbance in nervous system

159
Q
A

Tea, sea food, drinking water

160
Q

What are the deficiency symptoms of F?

A

Tooth decay