HUESO Flashcards

1
Q

Principal proteína de la matriz orgánica del hueso

A

Colageno 1

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2
Q

Principales proteínas de la matriz inorgánica del hueso

A

Ca+, P, Fosfato (cristales de hidroxiapatita)

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3
Q

Se encarga de la producción y síntesis de la matriz ósea

A

Osteoblasto (secreta colageno 1)

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4
Q

Se encarga del mantenimiento y remodelamiento de la matriz ósea

A

Osteocito

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5
Q

Deriva del monocito

A

Osteoclasto

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6
Q

Molecula que fija la matriz inorganica

A

Osteocalcina
(si no viene esa poner OSTEONECTINA)

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7
Q

Adhesión de las células a la matriz ósea

A

Osteopontina (sialoproteina BSP1)

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8
Q

Produce vesiculas matriciales de osteoide

A

Osteoblasto

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9
Q

Hace la RESORCIÓN ÓSEA

A

Osteoclasto

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10
Q

Captura el Ca+ desde la circulación hacia el hueso

A

Osteocalcina

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11
Q

Molecula que une la matriz orgánica con la inorgánica

A

Osteonectina

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12
Q

Dectecta la tensión mecánica

A

Osteocito

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13
Q

Moleculas que intervienen en la resorción ósea/hidrolisis enzimática

A

Anhidrasa carbonica, Captesina K, fosfatasa ácida, metaloproteasa

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14
Q

Inhibe la resorción ósea (RANK-L)

A

OPG (osteoprotegerina) secretado x el osteoblasto

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15
Q

Moleculas secretadas por el osteoclasto en la hidrolisis enzimática

A

Catepsina K y metaloproteasa

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16
Q

Interrumpe el mecanismo RANK-RANKL

A

Osteoblasto

17
Q

Activa INDERECTAMENTE al osteoclasto para que se produzca la resorción ósea elevando el Ca+ en sangre

A

PTH (Hormona paratiroidea)