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HTN > HTN Pathophysiology > Flashcards

HTN Pathophysiology Flashcards

1
Q

BP equals

A

cardiac output x systemic vascular resistance

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2
Q

Cardiac output equals

A

stroke volume x HR

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3
Q

What constitues stroke volume

A

preload
afterload
contractility

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4
Q

pacemaker cells are influenced by what

A

autonomic nervous system

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5
Q

what is positive chronotropy

A

sympathetic nervous system increase HR

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6
Q

What is negative chronotropy

A

parasmpathetic system decrease HR

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7
Q

What is dromotrophy

A

how quickly signal gets to ventricles

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8
Q

What is negative dromotrophy

A

decrease conduction velocity

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9
Q

What is positive dromotrophy

A

increase conduction velocity

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10
Q

Phase 4 action potential of pacemaker cells

A

Inward Na current

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11
Q

What medication affects phase 4 action potential of heart

A

Class II beta blockers
Class IV Non DHP CCBs

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12
Q

Phase 0 action potential of pacemaker

A

Inward Ca

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13
Q

What medication affects phase 0 action potential of heart

A

Class IV Non DHP CCBs

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14
Q

What is inotropy

A

how hard the heart pumps out to vasculature

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15
Q

What influences inotropy

A

preload
afterload
free cystolic calcium

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16
Q

What is preload

A

amount of blood in the ventricles

17
Q

What is the frank starling mechanism?

A

increase in end-diastolic volume increase contractility

18
Q

What is afterload

A

the arterial pressure that must be overcome

19
Q

Primary HTN

A

combo of risk factors

20
Q

Secondary HTN

A

renal disease
adreanl disease
sleep apnea

21
Q

Drugs that increase BP

A

Amphetamines
Cocaine
Decongestants
Erythopoiesis stimulating drugs
Immunosuppressants
NSAIDs
systemic steroids
alcohol
appetite suppressants
caffeine
Antidepressants

HTN (16 decks)

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