HTN Meds for Patient Specific Factors Flashcards

1
Q

Stable ischemic heart disease

A
  1. ACEi/ARB & BB
  2. add CCB if not controlled
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2
Q

Heart Failure Reduced Ejection Fraction (HFrEF)

A
  • Anything except CCB (esp NON DHP)
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3
Q

Heart Failure Preserved Ejection Fraction (HFpEF)

A

Based on symptoms
* Fluid overload: diuretics
* Elevated BP: ACEi/ARB
* Elevated HR: beta blockers

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4
Q

CKD

A

ACEi/ARB if…
* Stage 3+
* albuminuria

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5
Q

Renal transplant

A
  • CCB
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6
Q

Secondary stroke prevention

A

if BP ≥ 140/90 then…
* ACEi/ARB AND thiazide

if not then…
* ACEi/ARB or thiazide

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7
Q

DM

A

any first line option
* if albuminuria: ACEi/ARB

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8
Q

Atrial Fibrillation

A

ARB

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9
Q

Aortic disease

A

Beta blocker

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10
Q

Black patients

A

Thiazide or CCB (including DM)
if HF or CKD: follow those guidelines

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11
Q

Pregnancy

A

Methyldopa, nifedipine, or labetalol

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12
Q

Resistant HTN Steps

A
  1. Optimize therapy
  2. Switch to chlorthalidone or indapamide
  3. Add spironolactone
  4. If HR>70, add BB; if HR<70, clonidine or guanfacine
  5. Hydralazine
  6. Replace hydralazine with minoxidil
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13
Q

ACE

A
  • angioedema
  • cough
  • take at night
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14
Q

Beta blocker

A
  • masks hypoglycemia
  • exercise intolerance
  • do not stop abruptly
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15
Q

Aliskiren

A
  • musculoskeletal
  • diarrhea
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16
Q

Thiazide

A
  • uric acid
  • hypokalemia
  • sulfa allergy
  • CrCl > 30
17
Q

DHP CCB

A
  • Reynaud’s pts
  • peripheral edema
  • reflex tachycardia
18
Q

Non DHP CCB

A
  • angina pts
  • bradycardia
19
Q

Loop

A
  • CrCl<30
  • uric acid
  • hypokalemia
  • sulfa allergy
20
Q

Hydralazine

A
  • lupus-like symptoms (joint pain, generalized weakness, fever)
  • use in severe CKD/hemodialysis
21
Q

Spironolactone

A
  • resistant HTN
  • gynecomastia
22
Q

Potassium-sparing

A
  • use in combo w/ thiazide
  • uric acid
23
Q

Diuretics in general

A
  • watch out for uric acid
  • hypokalemia (unless potassium-sparing or aldosterone receptor antagonist)
  • take in AM
24
Q

Anything that causes SE of hyperkalemia

A
  • avoid drugs that also cause hyperkalemia
  • don’t start if K>5
  • hold/reduce dose if K>5.5 or SCr increase >25%