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Host Defense > HSC differentiation: cells, growth factors, and cytokines > Flashcards

HSC differentiation: cells, growth factors, and cytokines Flashcards

1
Q

What are the 2 common progenitor cells that arise from HSCs

A

Common Myeloid cells

Common Lymphoid cells

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2
Q

Common myeloid progenitors include:

A

RBCs, granulocytes, and mononuclear cells

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3
Q

a mast cell is an example of what type of cell

A

granulocyte

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4
Q

a macrophage is an example of what type of cell

A

mononuclear cell

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5
Q

a basophil is an example of what type of cell

A

granulocyte

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6
Q

a neutrophil is an example of what type of cell

A

granulocyte

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7
Q

a myeloid dendritic cell is an example of what type of cell

A

mononuclear cell

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8
Q

an eosinophil is an example of what type of cell

A

granulocyte

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9
Q

Common lymphoid progenitors include

A

NK cells and Lymphocytes (T-cells, B-cells, and Plasma Cells)

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10
Q

What Growth Factors/ Cytokines produce Myeloid Progenitors

A

IL-3 & GM-CSF

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11
Q

What Growth Factors/ Cytokines produce lymphoid progenitors

A

IL-7

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12
Q

What Growth Factors/ Cytokines produce basophils

A

IL-4

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13
Q

What Growth Factors/ Cytokines produce neutrophils

A

G-CSF

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14
Q

What Growth Factors/ Cytokines produce Eosinophils

A

IL-5

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15
Q

What Growth Factors/ Cytokines produce Monocytes and Macrophages

A

GM-CSF and/or M-CSF

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16
Q

What Growth Factors/ Cytokines produce Dentritic cells

A

Flt3L

17
Q

What Growth Factors/ Cytokines produce T-cells

A

IL-2 and IL-7

18
Q

What Growth Factors/ Cytokines produce B-cells

A

a lot but mostly IL-3 and IL-7

19
Q

IL-3 and GM-CSF are important in the differentiation of what type of cells

A

Myeloid progenitor cells

20
Q

IL-7 is important in the differentiation of what type of cells

A

lymphoid progenitor cells

21
Q

IL-4 is important in the differentiation of what type of cells

A

Basophils

22
Q

G-CSF is important in the differentiation of what type of cells

A

neutrophils

23
Q

IL-5 is important in the differentiation of what type of cells

A

eosinophils

24
Q

GM-CSF and/ or M-CSF are important in the differentiation of what type of cells

A

monocytes and macrophages

25
Q

Flt3L is important in the differentiation of what type of cells

A

dendritic cells

26
Q

IL-2 and IL-7 are important in the differentiation of what type of cells

A

T-cells

27
Q

IL-3 and IL-7 are the main cytokines important in the differentiation of what type of cells

A

B-cells

Host Defense (1 decks)

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