HRCT

Question 1

DDx Perilymphatic

Answer 1

1. Sarcoidosis (patchy, asymmetric)
2. Silicosis (subpleural nodules are esp common, symmetric, posterior upper lobe predom)
3. Other pneumoconioses: CWP, Berylliosis, Talc
4. Lymphangitic spread of cancer (carcinoma, lymphoma)
5. Lymphoproliferative disease (LIP, Sjogren’s, multicentric Castleman, AIDS)
   - LIP can often mimic lymphangitic spread of cancer on HRCT
6. Amyloid, light chain deposition disease