HPV and Cervical Dysplasia

Question 1

Where do the most cases of cervical cancer occur?

Answer 1

LMIC

Question 2

What are the
1. 2 most virulent
2. 2 causing genital warts
forms of HPV?

Answer 2

1. 16 and 18

2. 6 and 11

Question 3

Risk factors for HPV infection

Answer 3

Early age of first coitus
Multiple sexual partners
Multiparity
Long term OC use
Immune compromise (steroids, smoking, renal failure, diabetes, HIV)

Question 4

9 types of HPV in 9-valent vaccine

Answer 4

6
11
16
18
31
33
45
52
58

Question 5

3 HPV vaccines

Answer 5

Bivalent (16 and 18)
Quadrivalent (6, 11, 16, 18)
Nonavalent

Question 6

Who gets HPV 8 free

Answer 6

Girls and boys in grade 6
Girls born in 1994 or later
HIV+ individuals 9-26
Transgender individuals 9-26
Males 9-26 who have sex with men, questioning orientation, or street involved
Males 9-18 in the care of MCFD or in youth custody services

Question 7

What makes a good screening tool?

Answer 7

Evidence that early detection improves health outcomes
An effective test is available
Diagnosis and treatment are available and acceptable
Benefits of screening outweigh potential harms
Prevalence of disease is high enough to justify the effort and costs of screening

Question 8

3 steps for diagnosing/treating cervical dysplasia

Answer 8

Pap smear
Colposcopy
Cervical dysplasia

Question 9

Cervical cancer screening in BC

Answer 9

Starts at age 25 or 3 years after first coitus (whichever is later)
Discontinue screening at age 69 (if 3 negative paps in the last 10 years)
Yearly until 3 negative results in a row, then every 36 months