How to use Antibiotics

Question 1

1. Identify the most appropriate antibiotics for treating staphylococcal infections.

Answer 1

likely not susceptible to synthetic penicillin

other options include TMP sulfa, clindamycin, minocylcine (inexpensive)

vancomycin is only IV, ceftaroline is very expensive

Question 2

2. List the commonly used antibiotic regimens for community-aquired pneumonia and rationalize the best choices based on spectrum of activity.

Answer 2

macrolides (erythromycin, azithromycin) good against atypicals and strep, weak H.flu

think about psuedamonas coverage

Question 3

3. Identify the most appropriate antibiotics for treating Pseudomonas.

Answer 3

cipro if susceptible and UTI
amino glycosides often show resistance due efflux pump (tobramycin)
carbapenems (doripenem) are active
cefepime (4th gen)/ ceftazamine