How do we see? Flashcards

1
Q

What is vision?

A

How we transduce light energy - assists with locating objects in collaboration with other senses

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2
Q

What happens to light as it enters the cornea to the retina?

A

It is refracted by the cornea and travels through the pupil and then refracted again by the lens

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3
Q

What is accommodation?

A

Eye muscles adjust lens curvature for focusing on objects at different distances.

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4
Q

What is significant about the curvature of the cornea?

A

Its fixed

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5
Q

What causes vision problems?

A

When the focal point of light refraction is in front or behind the retina

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6
Q

What causes astigmatism?

A

cornea or lens is rugby-ball shaped, not rounded. This prevents part of it from focusing light onto the retina. The result is a blurred area within an otherwise clear image.

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7
Q

What is the emmetropic eye?

A

normal vision

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8
Q

What is hyperopia and what are the cause and correction?

A

long-sighted vision (the hypermetropic eye) - the lens is too weak/eyeball is too short/cornea is too flat.
Can be corrected by a converging lens

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9
Q

What is myopia and what are the cause and correction?

A

short-sighted vision (the myopic eye) - lens is too strong/eyeball too long/cornea too curved
Can be corrected by a diverging lens

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10
Q

What is presbyopia and what are the cause and treatment?

A

The ability to see things up-close getting worse with age (presbyopic eye) - lens no longer flexible enough for accommodation
Corrected by reading glasses

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11
Q

What is the retina composed of?

A

Photoreceptors with a layer of neurons connected on top. These neurons are transparent so light can pass through, which is translated to action potentials

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12
Q

What is the fovea?

A

The centre of the retina & vision field - 0.3mm dimple in retina with denser receptors at centre. Sharpest vision, densest colour receptors (better than periphery) and makes reading possible

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13
Q

What is the blind spot?

A

An area of the retina with no photoreceptors where blood vessels enter and exit the eye. Fibres leading from retinal neuron form optic nerve going to the brain

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14
Q

What do photoreceptors do?

A

Convert light to chemical energy and then neural activity - light triggers chemical reactions - change membrane potential (electric charge)

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15
Q

What are the 2 types of receptors?

A

Rods - longer, cylindrical shape at one end ~ 120million
Cones - tapered at end 6-7million

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16
Q

What are the 6 ways photoreceptors are connected to ganglion cells?

A
  1. Horizontal cells
  2. Glial gells
  3. Amacrine cells
  4. Bipolar cells
  5. Rods
  6. Cones
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17
Q

What is colour vision enabled by?

A

Three cone types (red, green, blue).
Different combinations interpret a wide range of colors.
Roughly equal red and green
Less blue - not as sensitive

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18
Q

What is what colour we see determined by?

A

The absorption range of photoreceptors

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19
Q

How do we see a range of hues across visual field?

A

Cones are distributed across field of vision

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20
Q

Which chromosome are cones coded on and what implications does this have?

A

x-chromosome meaning that men are more likely to be colour-blind and women can have more distinctive colour vision than men because of an extra red pigment

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21
Q

What are the 4 types of neurons in retina?

A
  1. bipolar
  2. horizontal
  3. amacrine
  4. ganglion cells
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22
Q

How are retinal neurons arranged?

A

2 layers going from rods and cones to retinal surface

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23
Q

What are the 2 categories of retinal ganglion cells in primates?

A

Magnocellular (M-cells) and parvocellular (P-cells) cells

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24
Q

What are M-cells sensitive to and where do they get their information from?

A

Sensitive to light, movement and low contrast NOT colour or fine detail and get info mostly from rods

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25
Q

Where are M-cells present?

A

throughout retina, including periphery.
Axons (mostly) project to magnocellular layer of lateral geniculate nucleus

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26
Q

What are P-cells sensitive to and where do they mostly get their info from?

A

Sensitive to colour and fine detail (weak response to changes in contrast), info mostly from cones

27
Q

Where are P-cells present?

A

Mostly in fovea
Axons project to parvocellular layer of lateral geniculate nucleus

28
Q

What are receptive fields?

A

The region of space in which stimuli will alter a sensory neuron’s firing rate

29
Q

What characterizes neurons at different levels of processing in the visual system?

A

Neurons at different levels of processing in the visual system exhibit varying receptive fields, influencing their response to stimuli.

30
Q

How many types of receptive fields do bipolar cells in the visual system have, and how do they respond to light?

A

Bipolar cells in the visual system have two types of receptive fields, each responding differently to light.

31
Q

What are concentric receptive fields, and where do they play a role in the visual system?

A

Concentric receptive fields are a type of receptive field where stimuli alter a sensory neuron’s firing rate within a circular area.

32
Q

In on-centre receptive fields, how does the cell respond to light hitting the center, and what neurotransmitter is involved?

A

a light hitting the centre of its receptive field (receives less glutamate) excites the cell

33
Q

For off-centre receptive fields, what triggers the cell’s response, and which neurotransmitter is involved?

A

turning off light in the centre of its receptive field (receives more glutamate) excites the cell

34
Q

When there is bright light on centre, what happens in cells on-centre/off-surround field AND off-centre/surround field?

A

Excites cells on-centre/off-surround field and inhibits cells off-centre/surround field

35
Q

When there is bright light onto surrounding, what happens in cells on-centre/off-surround field AND off-centre/surround field?

A

Inhibits cells on-centre/off-surround field and excites cells off-centre/surround field

36
Q

When there is no illumination/diffuse illumination, what happens in cells on-centre/off-surround field AND off-centre/surround field?

A

Weak response from both (basal rate)

37
Q

How is shape coded in the retina?

A

Cells in the retina cant detect shape - their receptive fields are tiny dots that respond to presence/absence of light (info about luminance contrast) related to the arrangement of the cells’ receptive field - helps to detect edges

38
Q

What do the retinal cell ganglia form?

A

The optic nerve

39
Q

Where do the pathways from each eye intersect?

A

The optic chiasm

40
Q

What happens to the medial path of each retina (nasal) at the optic chiasm?

A

It crosses to the opposite side.

41
Q

What happens on the lateral (temporal) visual pathway?

A

Stays in the ipsilateral side

42
Q

What is the consequence of the crossing paths at the optic chiasm?

A

Information from each visual field is represented on the opposite side of the brain.

43
Q

What is the Geniculostriate system in the visual pathway?

A

It is a pathway where all P ganglion cells and some M ganglion cells separate from retinal cell ganglia axons. It extends from the retina to the lateral geniculate nucleus of the thalamus and then to layer 4 of the primary visual cortex (striate cortex) in the occipital lobe.

44
Q

What information does the Geniculostriate system convey to the visual cortex?

A

It carries information about color, form, and motion to the visual cortex.

45
Q

What characterizes the Tectopulvinar system in the visual pathway?

A

It is another pathway formed by the remaining M ganglion cells. Axons from this system travel to the superior colliculus (tectum) in the midbrain, and from there, connections are sent to the pulvinar region of the thalamus.

46
Q

Where does the Tectopulvinar system send information after reaching the pulvinar region of the thalamus?

A

The pulvinar sends information to the parietal and temporal lobes.

47
Q

What is the primary visual area (v1, striate)?

A

First stage of cortical processing of visual information.
Located in and around the calcarine fissure in the occipital lobe.
Retinotopic: Contains a complete map of the visual field covered by the eyes
V1 neurons are selective for basic visual properties: position, orientation, spatial and temporal frequency

48
Q

What characterises the extrastriate area V2?

A

Cells are tuned to similar properties as V1; spatial map.

49
Q

What characterises the extrastriate area V3?

A

receives input from V1 and V2; dorsal part projects to parietal cortex;
ventral part to inferior temporal cortex.

50
Q

What characterises the extrastriate area V4?

A

receives input from V1 and V2; strong projects to inferior temporal
cortex. Colour vision and simple shapes.

51
Q

What characterises the extrastriate area V5?

A

(mid-temporal visual area, MT): receives input from V1, V2 and V3.
Major role in the perception of motion.

52
Q

What is the ventral pathway?

A

Visual stream known as the what pathway - for form and colour.
Retinal P-cells → Parvocellular LGN → V1 → V2 → V4→ Inferior Temporal Cortex

53
Q

What is the dorsal pathway?

A

Visual stream known as the where pathway - for space and motion.
Retinal M-cells → Magnocellular LGN → V1 → V2 → V3 → V5/MT →
Posterior Parietal Cortex

54
Q

What is the significance of brain regions along the ventral and dorsal streams in visual processing?

A

These regions have specialized visual functions.

55
Q

In the temporal lobe, what specific pathway is associated with processing information about ‘what’?

A

The ventral pathway.

56
Q

What is the role of the Fusiform Face Area (FFA) in visual processing?

A

It is specialized for processing faces

57
Q

What is the specialized function of the Parahippocampal Place Area (PPA) in visual processing?

A

It is specialized for processing places.

58
Q

In the parietal lobe, what specific pathway is associated with processing information about ‘where’?

A

The dorsal pathway.

59
Q

What role do areas in the Intraparietal Sulcus play in visual processing?

A

They are involved in controlling eye movements and visual control of grasping.

60
Q

What is Optic Ataxia, and what brain region is implicated in this condition?

A

Optic Ataxia is a high-order deficit in visual reaching related to lesions in the posterior parietal cortex (PPC).

61
Q

What is Motion Blindness, and which brain area is affected in patient ‘LM’?

A

Motion Blindness results from damage to MT (middle temporal area), and patient ‘LM’ experienced this condition.

62
Q

What is retinotopic mapping in visual processing?

A

It is the organization of neurons in lower visual areas according to the 2D representation of the image formed on the retina.

63
Q

What does retinotopy involve?

A

remapping of retinal image onto cortical surface
Each point of the visual field maps onto a local group on neurons in V1
Neighbouring regions of the image are represented by neighbouring regions
of cortex
Representation is distorted; fovea represented by larger area (greater
magnification factor)