Hospital acquired infectons Flashcards
Most common syndrome of HAI
Hospital acquired pneumonia
Common UTI organisms in hospital
E.coli
Klebsiella
Proteus
Pseudomonas
resistance mechanisms of gram negatives (E. coli, Kleb, enterobacter)
chromosomal
plasmid mediated
what are gram negatives most resistant to
extended spectrum beta-lactamases
What dos it mean if you see gram positive cocci in clusters
stapholococcus (mainly staph aureus)
If a culture is resistant to oxacillin what does it mean
It is methicillin resistant (it is the lab marker when screening for resistance on plates
Organisms associated with catheter associated blood infections
MRSA
R gram negatives
MSSA
yeast/candida
Organisms - catheter associated UTI
Yeasts/candida
E.coli
R gram negatives
MRSA
Organisms - surgical site infection
MSSA
MRSA
R gram negatives
Organisms - ventilator associated pneumonia
E. coli
R gram negatives
Organisms - Abx associated diarrhoea
C. Diff
Spores germinate in gut, flora disturbed with Abx use
C. diff - toxins produced, Sx, mechanisms of tissue damage
Produced toxins A and B
Sx - diarrhoea, colitis
Pro-inflammatory, cytotoxic (Cell damage), enterotoxic (gut damage)
Drug and non drug Tx for for C diff
Abx - Fidaxomicin - macrolide Abx
Faecal transfer - filtered fresh faeces in saline from healthy donor
