Hospital Flashcards
CURB65 3-5 PA
IV Levofloxacin 500mg bd monotherapy
Non-severe HAP
PO Amoxicillin 5 days
Non-severe CDI
Metronidazole PO 400mg tds (10 days)
CURB65 3-5
Co-amoxiclav IV 1.2g tds + Doxycycline PO 100mg bd
CURB65 0-2
Amoxicillin 1g tds IV/PO (5 days)
CURB65 0-2 PA
Doxycycline PO 200mg on day 1 then 100mg od or IV Clarithromycin* if NBM)
Acute exacerbation of COPD
1 ST LINE Amoxicillin 500mg tds 2 ND LINE Doxycycline 200mg on day 1 then 100mg od (5days)
ICU/HDU CAP or NBM CAP
Co-amoxiclav IV 1.2g tds + Clarithromycin* IV 500mg bd
Endocarditis native valve severe sepsis
Flucloxacillin IV 2g 6 hourly (4 hourly if >85kg)
Spontaneous bacterial peritonitis severe
Piperacillin/Tazobactam IV 4.5g tds
Step down to co-trimoxazole PO
Endocarditis: prosthetic valve or Suspected MRSA
Vancomycin IV + Gentamicin + when therapeutic vancomycin levels reached add Rifampicin PO 600mg bd
Peritonitis/biliary tract/intra abdominal
IV Amoxicillin + Metronidazole + Gentamicin
CURB65
Confusion? Urea >7mmol? RR >30? BP <90/60?
Severe CDI
Vancomycin 125mg qds PO/NG +/- IV Metronidazole (10 days)
Endocarditis native valve subacute
Amoxicillin IV 2g 4 hourly + Gentamicin
CDI severity
One or more of: Temp >38.5, Ileus, Colonic dilatation >4cm, Toxic Megacolon, Pseudomembraneous Colitis, WBCC >15, Rising creatinine >1.5x baseline, persisting symptoms and +test despite 2 courses appropriate therapy
Severe HAP
Amoxicillin IV (Co-trimoxazole), Gentamicin
Spontaneous bacterial peritonitis non-severe
Co-trimoxazole PO
Complicated UTI/Pyelonephritis/Urosepsis
IV Amoxicillin + Gentamicin (If penicillin allergic: IV Co-trimoxazole + Gentamicin)
Uncomplicated female LUTI
2nd Line Nitrofurantoin 100mg MR bd (3 days)50mg qds
2nd Line Trimethoprim 200mg bd (3 days)
Uncatheterised male LUTI
1st lineNitrofurantoin 100mg MR bd (7 days) 50mg qds
2nd line Trimethoprim 200mg bd (7 days)
Severe systemic infection unknown origin
IV Amoxicillin + Metronidazole + Gentamicin
Open fracture prohpylaxis
Cefuroxime 1.5g IV every 8 hours
Cellulitis
Flucloxacillin 1g qds (If penicillin allergic: Doxycycline 100mg bd PO)
Mild diabetic foot infection
Flucloxacillin 1g qds or Doxycycline 100mg bd
Moderate diabetic foot infection
Flucloxacillin 1g qds + Metronidazole 400mg tds
OR Doxycycline 100mg bd + Metronidazole 400mg tds
Acute septic arthritis/osteomyelitis
IV Flucloxacillin 2g qds
Epiglottitis/supraglottitis
Ceftriaxone IV 2g od
Meningitis
Ceftriaxone IV 2g bd + Dexamethasone IV 10mg qds