hormonii tiroidieni Flashcards

1
Q

Etapele biosintezei hormonilor tiroidieni:

A
  1. captarea iodului din plasma
  2. organifierea iodului => MIT si DIT
  3. cuplarea resturilor de MIT si DIT => T3 si T4 atasati de tireoglobulina
  4. endocitoza tireoglobulinei din coloid in celulele foliculare, hidroliza proteinei si eliberarea T3 si T4 in sange
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2
Q

Organifierea iodului are loc cu enzima:

A

tireoperoxidaza dependenta de NADPH+H+

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3
Q

Hormonii tiroidieni sunt degradati in special prin:

A

indepartarea iodului in ficat, rinichi, muschi si alte tes

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4
Q

Secretia T3 si T4 din tireoglobulina este controlata de:

A

axa hipotalamo-hipofizara prin feed-back negativ

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