Hormones, the skeleton and HRT Flashcards

1
Q

Which hormones have skeletal effects?

A
oestrogen
parathyroid hormone
vitamin D
calcitonin
fibroblast growth factor 23
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2
Q

What are the 2 parts of bone?

A

cortical and trabecular

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3
Q

What is cortical bone like?

A

sheet like structure
in the shaft of the bone
on outer part of head of long bone
made of osteons

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4
Q

What is trabecular bone known as?

A

Spongy/cancellous

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5
Q

What is trabecular bone like?

A

inside the heads of long bones

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6
Q

Where do osteoclasts derive from?

A

haematopoeitic stem cells

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7
Q

Where do osteoblasts derive from?

A

mesenchymal stem cells

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8
Q

Where do osteocytes derive from?

A

mesenchymal stem cells

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9
Q

What do haematopoeitic stem cells give rise to?

A

immune cells
osteoclasts
blood

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10
Q

What are osteoblasts?

A

bone forming cells

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11
Q

What do osteoblasts do?

A

secrete organic matrix (osteoid formed of collagen)

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