Hormones Of GIT

Question 1

CCK

Answer 1

Secreted when chyme (especially when it is high in lipids no partially digested proteins) enters duodenum
In pancreas - accelerates production and secretion of digestive enzymes
Causes relaxation of hepatopancreatic sphincter & contraction of the gallbladder - ejection of bile and and pancreatic juice into the duodenum
Inhibits gastric activity and emptying
Affects CNS - reduces sensation of hunger

Question 2

GIP

Answer 2

Secreted when fats and carbohydrates (especially glucose) enter small intestine
Inhibits gastric activity
Stimulates insulin release
Stimulates duodenal gland activity
Stimulates lipid synthesis in adipose tissue
Increases glucose use by skeletal muscles

Question 3

VIP

Answer 3

Stimulates secretion of intestinal glands
Dilates regional capillaries
Inhibits acid production

Question 4

Secretin

Answer 4

Released from enteroendocrine cells
Released when chyme enters duodenum
Stimulates secretion of bile (by liver)
Stimulates secretion of buffers (by pancreas)
Reduces gastric motility and secretory rates

Question 5

Enterocrinin

Answer 5

Stimulates mucin production by submucosal glands

Question 6

Somatostatin

Answer 6

D cells

Inhibits contractions of stomach

Question 7

Gastrin

Answer 7

G cells
Duodenum and stomach
Exposed to large quantities of incompletely digested proteins
Increases stomach motility
Stimulates production of gastric acid enzymes 
Stimulates secretion of HCl
Stimulates growth of mucosal cells
Stimulates insulin secretion