Hormones - Function Flashcards
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TRH - Thyrotropin-Releasing Hormone
Stimulates anterior P.G. to release TSH.
CRH - Corticotropin-Releasing Hormone
Stimulates anterior P.G. to release ACTH. Acts as starter for stress response.
GnRH - Gonadotropin-Releasing Hormone
Stimulates anterior P.G. to release LH and FSH.
PIF - Prolactin-Inhibiting Factor
Inhibits PRL.
GH-IH - Growth Hormone Releasing Hormone
Stimulates anterior P.G. to release hGH.
GH-IH - Growth Hormone Inhibiting Hormone/Somatostatin
Inhibits hGH. Also inhibits Gastrin, CCK, Secretin, and Glucagon.
hGH - Somatotropin
Stimulates SKMT, cartilage, bone growth, by enlacing protein synthesis.
TSH - Thyroid Stimulating Hormone
Stimulates thyroid glands to secrete T3/T4.
FSH - Follicle Stimulating Hormone
Stimulates growth of ovarian follicles, plays role in menstruation and reproduction.
LH - Luteinizing Hormone
Triggers ovulation, helps produce Progesterone.
PRL - Prolactin
Stimulates engorgement of mammary glands with milk.
ACTH - Adrenocorticotropic Hormone
Stimulates adrenal glands to secrete certain adrenal hormones. `
MSH - Melanocyte Stimulating Hormone
Stimulates melanocytes to release melanin.
OT - Oxytocin
Stimulates myometrial contractions, milk ejection, rises in both men and women during orgasm; the “love” hormone.
ADH/VP - Vasopressin
Stimulates aquaporins in DCT/collecting ducts, allowing for reabsorption of water.
T3 - Triiodothyronine
Stimulates basic metabolic rate, increased heart rate and force of contraction, increased body temperature. Active form.
T4 - Thyroxine
Stimulates basic metabolic rate, increased heart rate and force of contraction, increased body temperature. Inactive form.
CT- Calcitonin
Lowers calcium levels by inhibiting osteoclasts and reducing absorption in the small intestine. Increases excretion from kidneys.
PTH - Parathyroid Hormone
Increases blood calcium levels by stimulating osteoclasts. Decreases excretion from kidney. Opposite of CT.
ALD - Aldosterone
Stimulates sodium reabsorption in collecting ducts, saving water.
Cortisol
Stress hormone; stimulates metabolism during stress.
DHEA - Dehydroepiandrosterone
Converts to sex hormones stimulating pubic/axillary hair during puberty.
Epinephrine - Adrenaline
Enhances the affects of the sympathetic nervous system. Used for many reasons including cardiac arrest and anaphylaxis.
Melatonin
Controls circadian rhythm.
Cholecalciferol
Increases rate of calcium, magnesium, and others in small intestine.
Gastrin
Stimulates chief and parietal cells; promote mixing; contract lower esophageal sphincter and relax pyloric sphincter.
Intrinsic Factor B12
Required for absorption of vitamin B12 in duodenum.
Motilin
Stimulates migratory motility complex.
Ghrelin
Appetite stimulator.
Serotonin
Increases local peristalsis; vasoconstriction of damaged tunica media.
Intestinal Gastrin
Stimulates chief and parietal cells; promote mixing; contract lower esophageal sphincter and relax pyloric sphincter. SIMILAR TO STOMACH GASTRIN.
Secretin
Triggers release of livers-gallbladder/pancreatic secretions to neutralize acidic chyme.
GIP - Gastric Inhibitory Peptide
Triggers release of insulin in presence of fats/carbs, especially glucose; reduces stomach activity.
CCK - Cholecystokinin
Causes Sphincter of Oddi to relax, allowing for pancreatic secretions to enter; gallbladder contracts; appetite suppressant; reduces stomach activity.
VIP - Vasoactive Intestinal Peptide
Stimulates intestinal glands; dilates capillaries; inhibits HCI production in stomach.
Insulin
Decrease blood glucose levels through absorption of glucose from blood to metabolically active cells.
Glucagon
Increases blood glucose levels through glycogen catabolism in liver.
Osteocalcin
Many purposes. Bone remodeling, regulation of bone absorption, endocrine effects, brain function and cognition, potential role in male fertility.
Leptin
‘Satiety hormone’; reflective of total body fat, when lower, stimulates eating and vice versa.
Renin
Enzyme that triggers the conversion of angiotensinogen to angiotensin I.
EPO - Erythropoietin
Stimulates release of RBC’s from bone marrow.
ANP/BNP- Atrial Naturetic Peptide and and Brian Naturetic Peptide
Inhibits Na+ and ultimately water reabsorption; inhibits ALD, ADH; peripheral vasodilation.
Angiotensinogen
Circulating angiotensin precursor.
Angiotensin I
Vasodilates.
Angiotensin II
Converted from Angiotensin I by ACE, vasoconstricts.
Thymosins
Stimulates T-Lymphocytes maturation.
Testosterone
Spermatogenesis, maintains male secondary sex characteristics, increases bone and muscle growth, maintains libido.
ABP - Androgen Binding Protein
Increases artificially the amount of androgens in lumen of seminiferous tubules for spermatogenesis.
Inhibin
Inhibits FSH, and possibly LH and GnRH, production in anterior P.G.
Estrogens
Oogenesis; maintains female sex characteristics and increases bone growth, maintains libido; lowers circulating cholesterol; creates infertility in men due to reduced fluid reabsorption in rete testes and efferent ductules (sperm too dilute.)
Progesterone
Stimulates growth of and maintains endometrial lining of uterus.
Relaxin
Relaxes myometrium for implantation initially; dilates cervix, releases myometrium and cartilaginous joint of pubic symphysis during birth.
hCG - Human Chorionic Gonadotropin
Signals implantation of the embryo stimulating the maintenance of the corpus luteum in the ovary of 4-5 months.
hPL/hCS - Human Placental Lactogen/Human Chorionic Somatomammotropin
Stimulates engorgement of mammary glands with milk; fetal nutrition.