Hormones Flashcards
growth hormone (hGH)
Gland: Anterior Pituitary
Class: Peptide
Target/Effect: Increase bone and muscle growth, increase cell turnover rate
Adrenocorticotropic Hormone (ACTH)
- Gland: Anterior Pituitary
- Class: Peptide
- Target/Effect: Increases growth and secretory activity of adrenal cortex
Thyroid Stimulating Hormone (TSH)
- Gland: Anterior Pituitary
- Class: Peptide
- Target/Effect: Increases synthesis and release of TH
Follicle Stimulating Hormone (FSH)
- Gland: Anterior Pituitary
- Class: Peptide
- Target/Effect Promotes follicle development in the ovary, Promotes spermatogenesis in testes
Releasing and Inhibiting factors
Gland: Hypothalamus
Class: Peptide
Target/Effect: pituitary/modify activity
Prolactin
Gland: Anterior Pituitary
Class: Peptide
Target/Effect: mammary gland/milk production
Luteinizing Hormone (LH)
Gland: Anterior Pituitary
Class: Peptide
Target/Effect: ovary/ovulation, testes/testosterone synthesis (gonadrotropic)
Antidiuretic Hormone (ADH aka vasopressin)
Gland: Posterior Pituitary
Class: Peptide
Target/Effect: kidney/water retention
Oxytocin
Gland: Posterior Pituitary
Class: Peptide
Target/Effect: breast/milk letdown, uterus/contraction
Thyroid Hormone (TH, thyroxine)
Gland: Thyroid
Class: modified amino acid
Target/Effect: child: necessary for physical and mental development
adult: increase metabolic rate and temperature
Calcitonin
Gland: Thyroid C cells
Class: Peptides
Target/Effect: bone, kidney/lowers serum [Ca2+]
Parathyroid Hormone (PTH)
Gland: Parathyroid
Class: Peptide
Target/Effect: bone, kidney, small intestine/raises serum [Ca2+] = works with osteoclasts
Thymosin (children only)
Gland: Thymus
Class: Peptide
Target/Effect: T cell development during childhood
Epinephrine (adrenaline)
Gland: Adrenal Medulla
Class: Modified amino acid
Target/Effect: sympathetic stress response (rapid)
Cortisol (glucocorticoid)
Gland: Adrenal Cortex
Class: Steroid
Target/Effect:
- Long Term stress response: increase blood glucose, increase protein catabolism, decrease inflammation and immunity, etc.
Aldosterone (mineralcorticoid)
Gland: Adrenal Cortex
Class: Steroid
Target/Effect: kidney / increase Na+ reabsorption which leads to increase in blood pressure
Sex Steroids
Gland: Adrenal Cortex
Class: Steroids
Target/Effect: not important but an adrenal tumor can overproduce these, causing masculinization or feminization
Insulin (secreted by B cells)
Gland: endocrine pancreas (islets of langerhans)
Class: Peptide
Target/Effect: Decrease blood glucose / increase glycogen and fat storage (absent or ineffective in diabetes mellitus)
Glucagon (secreted by A cells)
Gland: Endocrine Pancreas (Islets of langerhans)
Class: Peptide
Target/Effect: Increase blood glucose / decrease glycogen and fat storage
Somatostatin (SS) [secreted by gamma cells)
Gland: Endocrine Pancreas (islets of Langerhans)
Class: Peptide
Target/Effect: Inhibits many digestive processes
Testosterone
Gland: Testes
Class: Steroid
Target/Effect: male characteristics, spermatogenesis
Estrogen
Gland: Ovaries/Placenta
Class: Steroid
Target/Effect: female characteristics, endometrial growth
Progesterone
Gland: Ovaries/Placenta
Class: Steroid
Target/Effect: endometrial secretion, pregnancy
Atrial Natriuretic Factor (ANF)
Gland: Heart
Class: Peptide
Target/Effect: Kidney / ↑ urination to ↓ blood pressure
Erythropoietin
Gland: Kidney
Class: Peptide
Target/Effect: Bone marrow / ↑ RBC synthesis
Salivary Amylase
- Breaks down a bond in polysaccharides (starch and glycogen)
- Found in the saliva (mouth)
Lipase
Breaks down fats
Goblet cells
Make mucous that serves as lining from stomach
Chief cells
Secrete pepsinogen
G cells
Secrete gastrin
Gastrin
Controls the release of HCl from parietal cells
Parietal cells
Secrete HCl to increase the acidity in the stomach
Pepsinogen
- Protease
- Zymogen, turns into pepsin
Gastric Juices
HCl + pepsin + hormones involved in digestion
Liver
Produces bile, does detox, makes Albumin, vitamin storage, glucose regulation
Gall Bladder
Hold bile (emulsifier)
Pancreas
Major digestive enzyme producer + Bicarbonate
Trypsinogen
Pancreatic, zymogen, turns to trypsin when activated by enterokinase, converts chmyotrypsinogen to chymotrypsin
Chymotrypsinogen
Pancreatic, hydrolyze peptide bonds, activated by trypsin to turn into chmytrypsin
Enterokinase
Small intestinal gland, converts trypsinogen to trypsin
Cholecystokinin (CCK)
- Produced in the small intestine
- Released in small intestine when food moves from stomach to small intestine
- Stimulates bile and pancreatic enzymes release
- Increase Satiety
Secretin
- Produced in the small intestine
- Inhibits gastric release
- Secretes water and bicarbonate to neutralize acidity in the small intestine