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Kidney Bean > Hormones > Flashcards

Hormones Flashcards

1
Q

aldosterone increases Na+ _________ where?

A

absorption

  1. distal convoluted tubule
  2. collecting duct
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2
Q

ANP _____ Na+ reabsorption

A

decreases

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3
Q

R-A system is stimulated by what? what is its response?

A

decrease in ECFV

increase in Na+ reabsorption

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4
Q

what hormone keeps P-Na constant?

A

AVP

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5
Q

neural strech receptors signal what hormones to regulate Na+?

A

AVP

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6
Q

atrial stretch receptors signal what hormones to regulate Na+?

A

AVP

ANP

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7
Q

atrial baroreceptors signal what hormone to regulate Na+?

A

AVP

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8
Q

duh moment: what is the difference between AVP/vasopressin and ADH?

A

nothing, silly. they are the same thing.

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9
Q

where does AVP work?

A

at NK2C channel in TA-LoH

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10
Q

what stimulates aldosterone secretion?

A

plasma K

angiotensin

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11
Q

what inhibits aldosterone?

A

plasma Na

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12
Q

what are the ways aldosterone increases Na+ reab? hint: 4 ways

A
  1. open Na channel in apical DCT, CD
  2. Na/Cl co-transporter
  3. synth of Na/K ATPase
  4. synth of ATP via Krebs Cycle for Na/K ATPase
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13
Q

is the affect of aldosterone on Na slow or fast?

A

slow

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14
Q

natriuretic peptide is also called

A

ANP, ANF, or ANH

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15
Q

what is the source of ANP? what stimulates secretion?

A

cardiac atria cells

when P-Na increases // direct stimulant is atrial distension

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16
Q

what are the two targets of ANP?

A

renal tubular segments

renal blood vessels

17
Q

how does ANP decrease Na reab? three ways, note the location.

A

@ tubule: inhibits Na reab
@ renal vessel: increases GFR :: inc Na excretion
@ adrenal cortex: inhibits aldosterone and renin secretion

18
Q

what 2 hormones does ANP inhibit?

A

aldosterone

renin

19
Q

how does ANP inhibit Na reab @ tubule?

A

by Na channel p’lation

20
Q

what makes AI?

A

JG cells

21
Q

what makes angioten converting enz?

A

lung

kidney

22
Q

what does angioten converting enz do?

A

AI –> AII

23
Q

what does renin do?

A

apha2-globin —> AI

24
Q

what are the two functions of AII?

A
  1. stimulate aldosterone production

2. stimulate Na reab in proximal tubule

25
Q

what produces aldosterone? what is the stimulus?

A

adrenal cortex

AII

26
Q

where does AII work?

A

the Na/H exchangers in the proximal tubule

27
Q

where does aldosterone work?

A

Na channel in DCT and CD

28
Q

what stimulates renin release?

A

low Cl- at JGA

Kidney Bean (2 decks)

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