Hormones Flashcards
Growth hormone (GH)
Increase bone and muscle growth, Increase cell turnover rate.
Secreted by Anterior pituitary
Prolactin
Target: Mammary gland
Effect: milk production
Secreted by Anterior pituitary
Thyroid stimulating hormone (TSH) (tropic)
Target: Thyroid
Effect: Increase synthesis and release to Thyroid hormone (TH)
Secreted by Anterior pituitary
Adrenocorticotropic hormone (ACTH) (tropic)
Increase growth and secretory activity of adrenal cortex
Secreted by Anterior pituitary
Luteinizing hormone (LH) (gonadotropic)
Ovary/ovulation, testes/testosterone synthesis
Secreted by Anterior pituitary
Follicle stimulating hormone (FSH) (gonadotropic)
Ovary/follicle development; Testes/spermatogenesis
Secreted by Anterior pituitary
Antidiuretic hormone (ADH, vasopressin)
Target: Kidney
Effect: Increase water retention
Secreted by Posterior Pituitary
Oxytocin
Target: Breast
Effect: milk letdown
Target: Uterus
Effect: contraction
Secreted by Posterior Pituitary
Also important in mediating social attachment between mother and child.
Thyroid hormone (TH, thyroxine)
Target: Child
Effect: necessary for physical and mental development
Target: Adult
Effect: Increase metabolic rate and temperature
Secreted by the thyroid
Calcitonin
Target: Bone, kidney
Effect: lowers serum [Ca2+]
Secreted by Thyroid C Cells
Parathyroid Hormone (PTH)
Target: Bone, kidney, small intestine
Effect: Raises serum [Ca2+]
Secreted by Parathyroid
Epinephrine
Sympathetic stress response (response to activation of the sympathetic nervous system)
Secreted by Adrenal Medulla
Cortisol (“glucocorticoid”)
Longer-term stress response
Increase blood [glucose]
increase protein catabolism
Decrease inflammation and immunity
Secreted by Adrenal Cortex (NOT MEDULLA)
The hypothalamic-pituitary-adrenal axis (HPA) involves the adrenal cortex, but not the adrenal medulla. The HPA regulates cortisol release from the cortex, not the medulla.
Aldosterone (“mineralcorticoid”)
Target: Kidney
Effect: Increase Na+ reabsorption to b.p.
Secreted by Adrenal Cortex
Insulin
Decrease blood [glucose]
Increase glycogen and fat storage
Secreted by beta cells from the islets of Langerhans in the endocrine pancreas
Absent or ineffective in diabetes mellitus
Type I diabetes doesn’t make insulin