Hormones

Question 1

ACTH (adrenocorticotropin)

Answer 1

Target organ= adrenal cortex, Zina fasciculata
Effect=mineral corticoids/glucocorticoids
Gluconeogenesis when under stress or not eating (breakfast)
Shuts down immune system
Excess=cushings
Deficiency = addisons

Question 2

FSH

Must be actively inhibited by inhibin

Answer 2

Target organs= ovary, testes
Effect= females release follicle, releases estrogen (proliferative phase) inhibin made by corpus leuteum
Males stimulates spermatogenesis , inhibin made by Sertoli cells
Excess: multiple oocytes
Deficiency: infertility

Question 3

Growth hormone aka somatropin

Answer 3

Target organs: all issues except cartilage
Effect: burn fat not carbs
Somatostatin release triggered by hypothalamus, shuts off somatotropin
Somatomedin from liver mediates growth hormone for cartilage
Excess: before puberty gigantism,after puberty acromegly
Deficiency: dwarfism

Question 4

Lutenizing hormone

Answer 4

Target organs: ovary, testes
Effect: female ovulation,forms corpus leuteum to make progesterone–> secretory phase
Male testosterone
Interstitial cells of leydig
Excess: forms corpus leuteum when levels up
Deficiency: degenerates corpus leuteum when levels down

Question 5

MSH secreted from pars intermedia

Answer 5

Target organs: melanocytes
Effect: basement layer of epidermis 
Stimulated by uv light
Excess: hyper pigmentation 
Deficiency: albinism

Question 6

Prolactin

Answer 6

Target organs: mammaries
Effect: makes milk, must be actively inhibited by dopamine
Excess: too much milk
Deficiency: too little milk

Question 7

Thyroid stimulating hormone

Answer 7

Target organ: thyroid follicular cells
Effect: thyroxin (T4)= 2 try rosiness +4 iodide
Triiodothyronine (T3) made from T4
T3 more powerful, faster acting, l so abundant than T4
Maintains BMR
Excess: graves,heat intolerance
Deficiency: cretinism,hashimoto, myxedema