hormones Flashcards
PTH
Parathyroid
Increase Ca2+ in blood
Calcitonin
Thyroid
Increase Ca2+ in bones
Oxytocin OXT
Hypothalamus
Contractions/birth, milk secretion, bonding
ADH
Hypothalamus
Conserve water
note: alco inhibits ADH
TSH
Ant. Pituitary
Metabolism
Prolactin
Ant. Pituitary
Milk production
FSH
Ant. Pituitary
spermatogenesis, follicle growth, ova maturation
LH
Ant. Pituitary
spermatogenesis, release testosterone, ovulation
ACTH
Ant. Pituitary
Release cortisol (stress) and Aldosterone (salt lover)
GH
Ant. Pituitary
Growth
TH
Thyroid
↑ metabolic rate, regulate tissue growth and development, BP by ↑ adregenic receptors
Aldosterone
Adrenal cortex
Salt lover, ↓ Na+ excretion (↑ K+ elimination)
Angio II
Converted by Ace
Stimulate release of aldosterone, vasoconstriction, stimulate the release of ADH, ↑ thirst
ANP/BNP
Heart/Brain
↓ BP by ↓ Na+, inhibit raas (blocks renin/aldosterone secretion). ANP also dilates coronary arteries.
Renin
Kidney (enzyme)
Activates raas, Converts angiotensinogen to angio I
ACE
Lungs (enzyme)
Convert Angio I to Angio II
Cortisol
Adrenal cortex
Stress. Gluconeogenesis, enhance symp vasoconstriction
E
Adrenal medulla
↑ HR, ↑ metabolic rate, ↑ BP (vasoconstriction)
NE
Adrenal medulla
↑ HR, ↑ metabolic rate, ↑ BP (vasoconstriction)
Testosterone
Gonads
Maturation of male reproductive organs, male scondary characteristics. Necessary for normal sperm production and maintainance of male repro organs.
Estrogen
Gonads
Maturation of reproductive organs, secondary female characteristics
Progesterone
Progesterone
Acting with progesterone, estrogen promote breast development and changes in uterine mucosa
Melatonin
Melatonin
Dracula hormone, rises at night, unknown - maybe sleep/wake
Glucogon
Pancreas
Hyperglycemic, breaks down glycogen to glucose, ↑ blood glucose
Insulin
Pancreas
↓ blood glucose, inhibits breakdown of glycogen to glucose, transport into cells
Leptin
Adipose
Advises brain of fat levels
EPO
Kidney
Signals bone marrow to ↑ RBC production
Resistin/Adiponectin
Adipose
Antagonize insulin/Enhance insulin
Osteocalcin
Skeleton ↑ insulin production/sensitivity
Cholecalciferol
Skin
Stimulates active transport of dietary calcium across cell membranes of small intestine
Calcitriol
(Cholecalciferol activated by kidneys)
Hormonally active metabolite of vit d. ↑ blood calcium levels
Thymulin/poietins/sins
Thymus
T lymphocyte development
GNRH
Hypthalamus
Stimulates release of LH and FSH
TPO
Liver/Kidney
Regulates formation of platelets
Hepcidin
Liver
Inhibits export of iron from cells
Motilin
Duodenal Mucosa
Stimulates migrating motor complex
Histamine
Stomach mucosa
Activates parietal cells to release HCl
Secretin
Duodenal mucosa
↑ bicarb secretion from pancreas, ↑ bile output from liver
Serotonin
Stomach mucosa
Causes contraction of stomach muscle
Somatostatin
Stomach/duodenal mucosa
Inhibits: gastric secretions, secretion, GI blood flow, contraction
VIP
Enteric neurons
Dilates intestinal caps, stimulates buffer secretion, relaxes intestinal smooth muscle, ↑ secretion, ↓ acid secretion
CCK
Duodenal mucosa
↑ enzyme secretion from pancreas, stimulates gallbladder to release bile, relaxes hepatopancreatic sphincter, inhibits stomach secretory action
GIP
Duodenal mucosa Inhibits HCl production, stimulates insulin release
Gastrin
Stomach mucosa/G cells
↑ HCl, Stimulates contraction of intestinal muscle, relaxes ileocecal valve, stimulates mass movements
Ghrelin
Stomach
Stimulates food intake
IGF
Liver
Growth promoting protein, acts as hormone (skeletal/muscle/bone IGFs act as paracrine)
Inhibin
Ovaries/testes
Inhibit production of FSH/GNRH
Adenosine
?
Dilate coronary arteries
Relaxin
Uterus
Causes pelvic ligaments/pubic symphysis to relax/widen/become flexible