Hormones Flashcards
What are hormones?
Hormones are chemical messengers produced in minute quantities by glands, transported in the blood to a target organ.
Classification of hormones ?
- Proximity of their site of synthesis to their site of action
- Chemical structure
- Solubility in an aqueous medium
What are the three classes of hormones based on the proximity of their site of synthesis to their action?
- Autocrine
- Paracrine
- Endocrine
What are the classification of hormones based on their chemical structure?
1.Peptide or protein hormones
2. Amino acid derivatives
3. Fatty acid derivatives
4. Steroid hormone derivatives
What are the classification of hormones based on their solubility in aqueous medium
- Lipophilic hormones
- Hydrophilic hormones
Three examples of hydrophilic hormones
- Insulin
- Glucagon
- Epinephrine
Example of lipophilic hormones
- Steroid hormones
- Thyroid hormones
What are peptide hormones?
Peptide hormones are hormones consisting of short chain amino acid
What are protein hormones
These are hormones consisting of a longer polypeptide.
Examples of protein hormones
Thyrotropin releasing hormone(TRH), Insulin and pituitary gonadotropins
Examples of amino acid derived hormones ?
Adrenaline, catecholamines and thyroid hormones
Example of fatty acid derived hormone ?
Eicosanoid (prostaglandin)
Example of steroid hormones
Estradiol, cortisol, aldosterone and testosterone
What are hydrophilic hormones
These types of hormones can’t cross the cell membrane, so they bind with receptors on the outer surface of the targeted cell
What are lipophilic hormones
Lipophilic hormones are hormones that can easily cross the cell membrane, enter their target cells and bind to intracellular receptors