Hormones Flashcards
Main estrogen in postmenopausal women who are not on HRT.
Estrone (E1)
Note: Anti-Estrogen therapy, adjunct assessment of fx risk, d/o of sex steroid metabolism, delayed or precocious puberty. Rarely drawn.
Major secretory product of ovary; fluctuates widely during menses and drops after menopause.
Estradiol (E2)
Note: Anti-Estrogen therapy, d/o of sex steroid metabolism, evaluate ovarian function, monitoring HRT, cirrhosis and hyperthyroidism.
Major estrogen in pregnancy. *Looks for complications in pregnancy.
Estriol (E3)
Note: Quad screen, fetal pathology, marker for fetal demise, assess PTL risk.
Gametogenesis and ovarian cycle.
FSH
Ovarian cycle and initial maintenance of luteal function for 1st 2wks. of pregnancy.
LH
In males, promotes testosterone synthesis.
FSH & LH
What happens if FSH & LH are high?
- Castration
- Ovarian hypofunction/hypogonadism
- Menopause
- Precocious puberty
What happens if FSH & LH are low?
- Pituitary failure
- Anorexia/malnutrition
- Pregnancy
- Hypothalamic failure
- OCPs
Initiation and maintenance of lactation.
Prolactin
Prolactin is inhibited naturally by _____.
Dopamine
Note: Any dopamine antagonist, serotonergic, anti-HTN drugs may increase Prolactin.
Progesterone in which organ/area of body?
- After ovulation
- Determines if ovulation occurred and menopausal status
Corpus Luteum
Progesterone in which organ/area of body?
- Secretory in pregnancy end of 1st trimester
- Evaluation of placental function in pregnancy
Placenta
Progesterone in which organ/area of body?
- Converts to other steroids
- Does NOT contribute to serum levels
- Use in tumor w/u of this area
Adrenal Gland
With menopause, there is…
- Less production of androstenidone (primary androgen in F.
- Decreased levels of testosterone.
Androgens
With menopause, there is…
- Reduced endogenous estrogen
- Greatest decrease in _____
Primarily secreted from adrenal.
Estrogen
Estradiol
