hormone receptors Flashcards
1
Q
what do G protein-coupled receptors respond to and activate?
A
respond extracellular signals
activate G proteins
2
Q
what do G proteins function as? how?
A
on-off switched for intracellular signalling pathways
by activating or inactivating ion channels or effector enzymes that generate second messenger molecules
3
Q
what is the structure of GPCR
A
7 transmembrane alpha-helical regions
N-terminus on outside of cell
C-terminus on cytosolic face
