Hormone action regulation Flashcards
3 different ways that stimulate hormone release are?
Hormonal: from another hormone
Neural: stimulation from nerve fibres
Humoral: level of substances in the blood
What affects the amplitude of the response by the target cell that a hormone acts upon?
- number of receptors
- affinity of hormone binding to receptor
- amount of hormone
what is permissiveness?
a hormone must be present to allow for another hormone to be effective
what is synergism?
hormones combined together have a greater effect than the sum of their separate effects
what is antagonism?
hormone reduces effects of another hormone
what are the factors that influence plasma hormone concentration?
MAIN: rate of secretion
- rate of binding
- rate of metabolism
what is clearance?
removal of hormone from plasma
what is half-life
time for which hormone drops to 50% of its concentration
What is hyposecretion
Too little hormone secreted
What is hypersecretion
Too much hormone secretion
Difference between primary and secondary disorder?
Primary: abnormality within the gland
Secondary: gland is normal. too little/much stimulation
