Hormonal reg of carb metabolism

Question 1

high blood sugar leads to increased

Answer 1

insulin

Question 2

insulin leads to dephosphorylation of

Answer 2

• PFK-2 (KINASE active = more F2,6BP)
• Pyruvate Kinase (active)
• Pyruvate dehydrogenase (E1 active)
• Glycogen synthase (active)
• Glycogen phosphorylase (inactive)

Question 3

insulin activates which pathways

Answer 3

glycolysis,
CAC,
Glycogen synthesis (Gycogenesis)

Question 4

low blood sugar leads to release of

Answer 4

glucagon

Question 5

Glucagon leads to phosphorylation of

Answer 5

• PFK-2 (PHOSPOHATASE active = less F2,6BP)
• Pyruvate kinase (inactive)
• Pyruvate dehydrogenase (E1 inactive)
• Glycogen synthase (inactive)
• Glycogen phosphorylase (active)

Question 6

Glucagon activates which pathways

Answer 6

• Gluconeogenesis

- Glycogen breakdown (Glycogenolysis)