Homework-Week 1 (Chapter 1)

Question 1

IACUC

Answer 1

Institutional Animal Care and Use Committee

Question 2

ACLAM

Answer 2

American College of Laboratory Animal Medication

Question 3

AALAS

Answer 3

American Association of Laboratory Animal Science

Question 4

FDCA

Answer 4

Federal Food, Drug and Cosmetic Act

Question 5

ILAR

Answer 5

Institute for Laboratory Animal Research

Question 6

NIH

Answer 6

National Institute of Health

Question 7

ASLAP

Answer 7

American Society of Laboratory Animal Practitioners

Question 8

NABR

Answer 8

National Association for Biomedical Research

Question 9

CMAR

Answer 9

Certified Manager Animal Resources

Question 10

FBR

Answer 10

Foundation for Biomedical Research

Question 11

Institutional Animal Care and Use Committee

Answer 11

Prior to use of animals, a protocol must be approved by this committee

Question 12

American College of Laboratory Animal Medication

Answer 12

Specialty board recognized by the AVMA

Question 13

American Association of Laboratory Animal Science

Answer 13

Nonprofit organization that serves as the principle means of communication between individuals and organizations within the field of laboratory animal science

Question 14

Federal Food, Drug and cosmetic Act

Answer 14

Passage of this law led to the product safety testing

Question 15

Institute for Laboratory animal Research

Answer 15

Develops guidelines and disseminates information on scientific, technological, and ethical use of animals

Question 16

National Institute of Health

Answer 16

Main public granting agency for biomedical research

Question 17

American Society of Laboratory Animal Practitioners

Answer 17

Professional organization for veterinarians engaged or interested in the practice of laboratory animal medicine

Question 18

National Association for Biomedical Research

Answer 18

Nonprofit organization dedicated to advocating sound public policy that recognizes the vital role of animal use in biomedical research

Question 19

Certified Manager Animal Resources

Answer 19

Certification program for managers of animal facilities

Question 20

Foundation for Biomedical Research

Answer 20

Nonprofit organization dedicated to promoting public understanding and support for the use of animals in research through educational materials

Question 21

Use of cell culture in oncology study

Answer 21

Replacement

Question 22

Giving non-steroidal anti-inflammatory drug in food for pain relief

Answer 22

Refinement

Question 23

Use mice rather than dogs in study

Answer 23

Replacement

Question 24

Corrsitex in vitro method used to determine the dermal corrosive potential of chemicals

Answer 24

Replacement

Question 25

Employ better statistical methods

Answer 25

Reduction

Question 26

Use tumor size as endpoint for study

Answer 26

Refinement

Question 27

Use excised porcine corneas that are normally discarded as waste in food production for ocular irritation assay

Answer 27

Replacement

Question 28

Use staircase design for study

Answer 28

Reduction

Question 29

Use computer design rather than rats

Answer 29

Replacement

Question 30

House primates in pairs or groups

Answer 30

Refinement

Question 31

Use multiple areas on back of pig for skin study

Answer 31

Reduction

Question 32

Fast rat for 8 hours rather than 16 hours before procedure

Answer 32

Refinement

Question 33

Use hollow fiber bioreactors for monoclonal antibody production instead of rabbit

Answer 33

Replacement

Question 34

Use Limulus Amebocyte Lysate Assay for pyrogens testing; blood is taken from horseshoe crabs who are then returned to the ocean

Answer 34

Replacement