homeostatsis Flashcards

1
Q

Homeostasis

A

set point

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2
Q

lack of homeostasis

A

forms basis of most diseases

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3
Q

adaptation

A

allows cells to survie short-term

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4
Q

cellular adaption

A

allows cells to survive short term

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5
Q

Physiological/pathological consequences if homeostasis isn’t returned.

A

r eversible cell injury-irreversible-cell death Most physiological process are goverened by negative feedback mechnisms exceptions are hemostatsis and parturition.

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6
Q

Morphologic charcteristics

A

Excessive cell swelling and dramatic changes to organelles. Hydrophic

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7
Q

Hallmark of irreversible cell injury or death

A

Massive Ca+ influx

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8
Q

Cell death

A

Necrosis

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9
Q

Apoptosis

A
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10
Q

Homeostasis

A

dynamic processe to response to stress or injury

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11
Q

Regulated Variables

A

have a physical receptor eg. temperature and BP

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12
Q

Afferent Pathway

A

information relayed via afferent to integrating center

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13
Q

Set point

A

range of normal values

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14
Q

Efferent pathway

A

carries departures from normal to alter controlled variables as part of effector response

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15
Q

Negative feedback

A

work to return the orginal input signal back to wnl.

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16
Q

Physical receptors

A

thermoreceptors, baroreceptors, chemoreceptors, osmo and mechanoreptors

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17
Q

controlled variables

A

vasoconstriction, vasodilation, increase heart rate, sweat reponse, muscle contraction

18
Q

Pathology

A

can be caused by intrinsic (genetic) or extrinsic environmental stress or injury.

19
Q

Genetic causes

A

mayh be inherited mutations from parent

20
Q

acquired

A

mutations from the environment

21
Q

diseases can be both

A

genetic and environmental

22
Q

diseases offer specific process

A

inflammation or autoimmunity

23
Q

etiology

A

underlying cause of disease

24
Q

Understanding disease process allow you

A

to inform, dx, rx, and prevent disease

25
Q

Down syndrome is not

A

inherited, acquired congenital during process

26
Q

Normal cell goes from

A

adapted, reversible cell injury, irreversible cell injury-cell death

27
Q

Atrophy

A

shrinkage of tissue or reduction in cell size

28
Q

Hypertrophy

A

increase in cell size in response to stress

29
Q

Hyperplasisa

A

increase in cell number

30
Q

Metaplasia

A

reversible process where one mature cell is replaced by another less mature cell type

31
Q

Type of cells that are replaced in smoking

A

Different type of lining, barrets esophagus

32
Q

Dysplesia

A

Disordered growth and maturation of cellular components of tissue

33
Q

Cellular accumulations and calcifications occur in response to injury and subsequent manifestations of cellular damage

A
34
Q

Under stress cells…

A

Accumulate substances,

35
Q

Acumulationg substances may lead to …

A

cell injury or cell death and provide INDICATIONS of cell injury

36
Q

Lipids are found in

A

heart and liver

37
Q

Glycogen

A

particular in liver and skeletal muscle

38
Q

Melanin

A

Melanocytes in the skin

39
Q

Hemosiderin

A

formed from hemoglobin-iron

40
Q

Bilirubin found

A

liver

41
Q

Hyaline change is

A

non-specfic indicator -formed from protein, seen cartilage, may intefere with metabolic or physical fx, thus tissue.

42
Q

Inflammatory response

A

can lead to further injury