Homeostatis Flashcards
Name 5 homeostatic mechanisms
-temp control
-blood pressure
-waste removal
-conc of nutrients in blood
-heart rate
What is homeostasis and its aim
-The ability of the body to maintain relatively stable internal conditions even when the environment is changing and the activity of the individual is changing.
-This is a dynamic equilibrium
-Aim: body is supplied with sufficient nutrition and oxygen in comfortable conditions & functioning well
The …….. system and the ………. System work together to control all homeostatic functions of the body.
Neural and endocrine
Process of homeostatic control requires communication from different parts of the body……
Receptors, stimuli, control centre (afferent and efferent pathways), effector
What are receptors?
-specialised cells that detect changes in internal and external conditions.
-send stimuli to the control centre
What is a stimuli?
The change detected is a stimulus.
What are the two different pathways in the control centre and define them.
1.-Afferent pathway: leads to the control centre
2.-Efferent pathway: leads from the control centre to the organ/ muscle which is then going to respond by secreting molecules or moving a part of the body -Will continue until a set point/ conc
What is an effector
include muscles and glands - that produce a specific response to a detected stimulus.
Homeostatic mechanisms can be …………… or …………… or ………. (Give an example of each one )
-neural e.g. reflex
-hormonal e.g. negative feedback
-both e.g. positive feedback
Step by step of the cooling mechanism
- The hypothalamus (the body’s thermostat) detects an increase in temperature.
- This triggers vasodilation (widening of blood vessels) and diaphoresis (sweating).
- These processes promote cooling, reducing the initial high-temperature stimulus.
Step by step of the warming mechanism
- The hypothalamus detects a drop in temperature.
- This triggers vasoconstriction (narrowing of blood vessels) and shivering (muscle activity generating heat).
- These responses help the body retain heat and increase temperature, counteracting the cold stimulus.
What are the hormones involved in negative feedback control
-CRF (Corticotropin-Releasing Factor) - Released by the hypothalamus.
-ACTH (Adrenocorticotropic Hormone) - Released by the anterior pituitary.
-Cortisol - Released by the adrenal glands.
How does the body respond to stress?
- Adrenaline (fight-or-flight hormone) is released:
o Heart beats faster (pulse increases).
o Blood pressure rises.
o Blood moves to muscles, and the liver releases extra energy (glucose). - Other Hormones Released:
o Cortisol: Helps the body deal with stress.
o Growth hormone: Repairs tissues and supports recovery.
o The hypothalamus and kidneys adjust water levels and blood pressure through other hormones like ADH and aldosterone.
CORTISOL
-glucose ( decreases/ increases)
-amino acids ( decrease/ increase)
- gluconeogenesis (decreases/ increases)
-protein break down to……….
-vasoconstriction (increases/ decreases)
-cartilage and bone formation ( decreases/ increases)
-blood pressure (increases/ decreases)
-inflammatory response (increases/ decreases)
-immune system (decreases/ increases)
-increases
-increases
-increases
-materials for growth and repair/ enzymes
-increases
-decreases
-increases
-decreases
-decreases
GROWTH HORMONE
-anabolic (…….. and ………. Promotion)
-fat breakdown and release (decreases/ increases)
-glycogenolysis and release (decreases/ increases)
-cartilage formation (decreases/ increases)
-Skeletal growth (decreases/ increases)
-protein synthesis, cell growth soft tissue (decreases/ increases)
- metabolic, growth
-increases
-increases
-increases
-increases
-increases
What is positive feedback and give an example of it
-when a response to a stimulus strengthens until the stimulus is completely gone
-e.g. contraction in childbirth and blood clotting
How does insulin regulate blood sugar levels?
When Blood Sugar is Too High:
1. The pancreas releases insulin.
2. Insulin helps:
o Cells absorb glucose from the blood.
o The liver stores extra glucose as glycogen.
3. Result: Blood sugar levels drop back to normal.
How does glucagon regulate blood sugar levels?
When Blood Sugar is Too Low:
1. The pancreas releases glucagon.
2. Glucagon helps:
o The liver breaks down stored glycogen into glucose.
o Glucose is released into the blood.
3. Result: Blood sugar levels rise back to normal.
INSULIN
1-promotes ………. ………… and ………. ……….
2-………. development in the brain
3-…….amino acid peptide, ……chains S-S bridges
4-……. …….. of pancreatic islets
1-protein synthesis, fat storage
2-neural
3-51, 2
4-beta cells
Insulin lowers blood glucose by……
-Enhances glucose uptake by cells, particularly muscle & fat cells
-Inhibits glycogenolysis - breakdown of glycogen
-Inhibits gluconeogenesis - conversion of amino acids or fats into glucose
GLUCAGON
1-……. amino acid peptide
2-………. …….. of pancreatic islets
3-decreased by high ……..conc, ………. and ………
4-primary target …….. cells
1-29
2-alpha cells
3-glucose, insulin, somatostatin
4-liver