Homeostasis & The Kidney Flashcards
What is homeostasis?
-The mechanism by which a constant internal environment is achieved
What are the two functions of the kidney?
- Removal of nitrogenous waste from the body
- Osmoregulation (the control of the water potential of the bodys fluids)
What is the structure of a section of the kidney?
- An outer cortex
- An inner medulla
- Which forms renal pyramids
- A pelvis at the centre which narrows to become the ureter
What are the three processes that happen in the kidney’s nephrons, and where do they take place?
- Ultrafiltration (in the glomerulus)
- Selective reabsorption (in the proximal convoluted tubule)
- Secretion (in the distal convoluted tubule)
What is the layer of cells surrounding capillaries in the glomerulus?
- Podocytes
- Have foot like processes known as pedicels
- Which have narrow spaces in between called slit pores
What is ultrafiltration?
-Filtering under high pressure that separates small molecules from the blood plasma
What does the filtrate in the Bowman’s capsule contain?
- Water
- Glucose
- Salts
- Urea
- Amino acids
What are some adaptations of the proximal convoluted tubule for selective reabsorption?
- Increased surface area due to the amount of tubules
- Increased surface area due to microvilli
- Lots of mitochondria to produce ATP
- Tight junctions between cells to prevent reabsorbed substances seeping back into the filtrate
How are substances reabsorbed during selective reabsorption?
- Most mineral ions reabsorbed by active transport
- All glucose and amino acids reabsorbed by co-transport with sodium ions
- Most water is reabsorbed by osmosis
- Some urea and some small proteins reabsorbed by diffusion
How does selective reabsorption happen in the loop of Henlé?
- Chloride ions actively transported out of the filtrate in the ascending limb, creating a low water potential in the medulla
- Water is drawn out the descending limb by osmosis to create a lower water potential at the bottom of the loop
- In the collecting duct, water is reabsorbed by osmosis as the medulla has a low water potential