Homeostasis & The Kidney Flashcards

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1
Q

What is homeostasis?

A

-The mechanism by which a constant internal environment is achieved

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2
Q

What are the two functions of the kidney?

A
  • Removal of nitrogenous waste from the body

- Osmoregulation (the control of the water potential of the bodys fluids)

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3
Q

What is the structure of a section of the kidney?

A
  • An outer cortex
  • An inner medulla
  • Which forms renal pyramids
  • A pelvis at the centre which narrows to become the ureter
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4
Q

What are the three processes that happen in the kidney’s nephrons, and where do they take place?

A
  • Ultrafiltration (in the glomerulus)
  • Selective reabsorption (in the proximal convoluted tubule)
  • Secretion (in the distal convoluted tubule)
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5
Q

What is the layer of cells surrounding capillaries in the glomerulus?

A
  • Podocytes
  • Have foot like processes known as pedicels
  • Which have narrow spaces in between called slit pores
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6
Q

What is ultrafiltration?

A

-Filtering under high pressure that separates small molecules from the blood plasma

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7
Q

What does the filtrate in the Bowman’s capsule contain?

A
  • Water
  • Glucose
  • Salts
  • Urea
  • Amino acids
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8
Q

What are some adaptations of the proximal convoluted tubule for selective reabsorption?

A
  • Increased surface area due to the amount of tubules
  • Increased surface area due to microvilli
  • Lots of mitochondria to produce ATP
  • Tight junctions between cells to prevent reabsorbed substances seeping back into the filtrate
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9
Q

How are substances reabsorbed during selective reabsorption?

A
  • Most mineral ions reabsorbed by active transport
  • All glucose and amino acids reabsorbed by co-transport with sodium ions
  • Most water is reabsorbed by osmosis
  • Some urea and some small proteins reabsorbed by diffusion
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10
Q

How does selective reabsorption happen in the loop of Henlé?

A
  • Chloride ions actively transported out of the filtrate in the ascending limb, creating a low water potential in the medulla
  • Water is drawn out the descending limb by osmosis to create a lower water potential at the bottom of the loop
  • In the collecting duct, water is reabsorbed by osmosis as the medulla has a low water potential
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