homeostasis and homeostatic integration Flashcards
define homeostasis
the tendency towards a stable equilibrium between interdependent elements, stabilised by physiological processes
what are the parameters for homeostatic control?
- pH
- ion concentration
- water
- small molecules
what is the pH and [Ca2+] in the cytosol?
pH 7.1
[Ca2+] 10-100nm
what is the pH and [Ca2+] in the mitochondrial matrix?
pH 7.7
[Ca2+] 1mM
what is the pH and [Ca2+] in the ECF?
pH 7.4
[Ca2+] 2mM
what is the [Ca2+] in the endoplasmic reticulum?
1mM
what is the pH range in the secretory vesicles?
5-6
what is the pH range in the lysosomes/endosomes?
4.6-6
what are the main differences between the ionic composition of the intracellular fluid and extracellular fluid?
intracellular fluid: low sodium, high potassium, low Cl, low HCO3 and really low Calcium
extracellular fluid: resembles seawater
what is meant by epithelia and what is its role?
the interface between the internal environment of the body and the external space. its job is to maintain volume and composition of the extracellular fluid
what is the equation for rate of solute movement?
J = P x (C1-C2)