homeostasis and homeostatic integration Flashcards

1
Q

define homeostasis

A

the tendency towards a stable equilibrium between interdependent elements, stabilised by physiological processes

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2
Q

what are the parameters for homeostatic control?

A
  • pH
  • ion concentration
  • water
  • small molecules
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3
Q

what is the pH and [Ca2+] in the cytosol?

A

pH 7.1

[Ca2+] 10-100nm

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4
Q

what is the pH and [Ca2+] in the mitochondrial matrix?

A

pH 7.7

[Ca2+] 1mM

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5
Q

what is the pH and [Ca2+] in the ECF?

A

pH 7.4

[Ca2+] 2mM

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6
Q

what is the [Ca2+] in the endoplasmic reticulum?

A

1mM

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7
Q

what is the pH range in the secretory vesicles?

A

5-6

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8
Q

what is the pH range in the lysosomes/endosomes?

A

4.6-6

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9
Q

what are the main differences between the ionic composition of the intracellular fluid and extracellular fluid?

A

intracellular fluid: low sodium, high potassium, low Cl, low HCO3 and really low Calcium
extracellular fluid: resembles seawater

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10
Q

what is meant by epithelia and what is its role?

A

the interface between the internal environment of the body and the external space. its job is to maintain volume and composition of the extracellular fluid

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11
Q

what is the equation for rate of solute movement?

A

J = P x (C1-C2)

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