`Homeostasis Flashcards
How is the intrinsic rhythm of the heart controlled
By impulses initiated in the sinoatrial node (SAN) and then spreads through the atrioventricular node (AVN) and the bundle of his to give a regular rhythm
What is the response of the heart to change as a result of
A result of the negative feedback system
When your body demands more glucose and oxygen what is one way your heart can respond
1)The rate at which the heart beats can increase and the volume of blood pumped at each heartbeat
how can the cardiac volume be increased
By a more efficient contraction of the ventricle
How can you calculate the cardiac output
Cardiac output = cardiac volume X heart rate
What happens to the heart during exercise
The heart rate begins to increase before the exercise begins. The cardiac volume increases more slowly, as it becomes clear from the changes in the body that exercise is going to continue
What is most of the nervous control in the heart
By the autonomic nervous system
How are nerve impulses sent to the cardiac centre
How does the cardiac centre respond
Chemicals, stretch and pressure receptors in the lining of the blood vessels and the chambers of the heart send nerve impulses to the cardiac centre
By sending impulses to the heart along parasympathetic and sympathetic nerves
How in the SAN stimulated
Nerve impulses travel down the sympathetic nerve from the cardiac centre in the brain to the heart to release noradrenaline
What does the stimulation of the SAN cause
an increase in the frequency of the signals from pacemaker region so heartbeats faster
What do impulses in the parasympathetic nerve release
what effect does this have
acetylcholine which inhibits SAN and slows the heart down
where are baroreceptors found
In the sinuses of the carotid arteries in the neck and on the aorta
What are baroreceptors important for
In feedback control of the heart rate during exercise
Explain what baroreceptors do during exercise
When exercise begins blood vessels dilate (vasodilation) in response to hormone adrenaline and blood pressure falls
What happens when stimulation from baroreceptors are reduced
The cardiac control centre immediately sends signals along the sympathetic nerve to stimulate the heart rate and increase blood pressure again by vasoconstriction
Explain what baroreceptors do when Excercise is stopped
Blood pressure in arteries increases as the heart continues to pump harder and faster than it needs to so baroreceptor is stretched. They send more sensory nerves via the parasymapthetic system to slow down the heart causing widening blood vessels
Where are chemoreceptors found
in the wall of the aorta and carotid arteries
what are chemoreceptors sensitive to
Carbon dioxide levels
What do chemoreceptors detect
Explain how this happens
As the level of CO2 increases the PH decreases which is detected by the aorta and carotid chemoreceptors
They send impulses along sensory neurons and to the cardiac control centre in the medulla, this increases the impulse traveling down the sympathetic nerve
What does the chemoreceptor do for the heart
It reduces the number of impulses to the cardiac centre reducing heart rate and makes it go back to the intrinsic rhythm
What does adrenaline stimulate
The cardiac centres in the brain, increasing the impulses in the sympathetic neurons supplying the heart, increasing frequency off excitation and so increasing the heart rate
What is osmoregulation
The maintenance of the osmotic potential in the tissues of a living organism within narrow limits by controlling water and salt concentrations
What are the cells of land-living mammals surrounded by
Tissue fluids that come from the blood capillaries
How can osmotic damage of cells be prevented
By controlling blood potential of blood the body can control the water potential of the tissue fluid
What’s the main organ involved in the water balance of the body
The kidney
What does lover play an important role in
In the deamination of excess amino acids in protein metabolism
What are hepatocytes and what does it do
liver cells and they deaminate excess amino acids
What do hepatocytes do to amino acids
They remove amino acid groups and convert it first to ammonia and then less toxic urea, which can be excreted by the kidney
What is the ornithine cycle
The process by which the ammonia produced from deamination of proteins
How is Osmoregulation brought about
What does it help us do
By the kidneys, which is more concentrated than the body fluids.
conserve water
How does the kidney look in humans
reddish brown organ attached to the back of the abdominal cavity
surrounded by a thick layer of fat (protects them from mechanical damage)
What do kidneys do
control the water potential of the blood that passes through them
Where Is the urine stored
in the bladder
What are the two main roles of the kidney
Excretion and osmoregulation
What are the three main functions carried out by the kidney in its osmoregulation role
Ultrafiltration, selective reabsorption and tubular secretion
What are nephrons
microscopic tubules that make up each kidney
What are the two main nephrons
what function do they carry out
Cortical nephrons
They have a loop of Henle that only just reaches into the medulla
Juxtamedullary nephrons
Have loop of Henle that penetrates right through the medulla
(particularly efficient for producing concentrated urine)
What’s the first stage of osmoregulation
What is it responsible for
Ultrafiltration
formation of tissue fluids
Why does ultrafiltration occur
Due to the combination of very high blood pressure in the glomerulus.
What makes up the malpighian body
The glomerulus and Bowmans capsule
Why does high blood pressure develop in the glomerular capillaries
The diameter of the blood vessel coming into the glomerulus is greater than that of the blood vessels leaving
What do the cells of Bowman’s capsule next to the capillaries act as
an additional filter
What are podocytes
Special cells that make up the wall of the capsule
What are pedicles
Extensions of the podocytes that wrap around the capillaries, forming slits that ensure any cells, platelets or large plasma proteins that have left the capillary do not get through into the tubule itself
What does the filtrate that enters the capsule contain
glucose, salt, urea and man other substances
Why is ultrafiltration described as passive and indiscriminative
it removes urea from the blood and but also removes a lot of water, glucose salt, and other substances
Why is glucose never ever excreted
It’s needed for cellular respiration
What is the main function if the kidney tubule after the ultrafiltrate has entered the nephron
To return to the most of what has been removed from the blood back to its rightful place