Homeostasis Flashcards

1
Q

What are Ectotherms?

A

Animals which gain heat from their surroundings

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are endotherms?

A

Animals like mammals and birds which generate their own heat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the control centre for thermoregulation?

A

The heat loss and heat gain centres in the hypothalamus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What centre activates when CORE temperature rises above the set point?

A

The heat loss centre

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

List thermoregulatory responses to core temp rising

A

Heat loss centre causes:

  • Vasodilation so heat is lost by radiation through skin
  • Sweat produced which evaporates. Carries lots of heat because water has a high latent heat of evaporation
  • Behavioural Responses
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

List thermoregulatory responses to core temp decrease

A

Heat gain centre causes:

  • Vasoconstriction causing blood to be redirected to shunt vessel, reducing heat loss by radiation
  • Skeletal muscles contract and relax repeatedly generating heat from friction and metabolic reactions
  • Non Shivering Thermogenesis occurs in Brown Adipose Tissue
  • Behaviour
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How do Ectotherms control temperature?

A

Only Behavioural responses, e.g. Sitting in sun or on hot surface to gain heat, going to shade to decrease temp, changing their angle in relation to the sun.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the three sources of glucose for the body?

A
  • Digestion of dietary carbohydrates
  • Gluconeogenesis
  • Conversion of glycogen to glucose
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the control centre for blood glucose homeostasis?

A

The Pancreas.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the two types of thermoregulators?

A

Endotherms and Exotherms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the receptors and effectors for blood glucose regulation?

A

The islets of Langerhans act as both

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the two kinds of cells in the Islet of Langerhans and what do they do?

A

Alpha cells release glucagon when they detect low blood glucose levels.
Beta cells release insulin when they detect high blood glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What effect does insulin have on liver and muscle cells?

A

Increases the rate of Glycogenesis (Conversion of Glucose to Glycogen) in both muscle and liver. Increases rate of lipogenesis in liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What effect does insulin have on cells?

A

Insulin increases uptake of glucose by cells by stimulating the recruitment of more glucose transporters to the cell membrane from the inner membrane pool

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What effect does glucagon have in the liver?

A

Glucagon increases the rate of glycogenolysis and Gluconeogenesis in the liver. (The rate of breakdown of glycogen to glucose and the rate of synthesis of glucose from non carbs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Explain the second messenger model for hormones such as insulin

A

Insulin binds to a receptor protein in the cell membrane which activates a G protein inside the cell that binds to and activates the enzyme Adenylate Cyclase which converts ATP to cAMP (the second messenger). cAMP then activates other proteins in a signal cascade leading to a cellular response such as conversion of glucose to glycogen

17
Q

Why is a second messenger necessary?

A

Hormones (apart from steroids) are not lipid soluble and so cannot diffuse through the phospholipid bilayer of the cell membrane

18
Q

Adrenaline binds to receptors in the plasma membranes of liver cells. Explain how this causes the blood glucose concentration to increase

A

Adenylate cyclise is activated which activates enzymes in the cell so glucoeogenisis and glyogenolysis occurs

19
Q

Explain how the formation of glycogen from glucose in liver cells leads to a lowering of blood glucose concentration. (2 marks)

A
  1. Glucose concentration in cell/liver falls;
  2. Below that in blood (plasma)/ higher in blood;
  3. Creates/maintains glucose concentration/diffusion gradient;
  4. Glucose enters cell/leaves blood by facilitated
    diffusion/via carrier(protein)/channel (protein
20
Q

Increased intensity of exercise leads to an increased heart rate. Explain how.

A

Carbon dioxide detected by chemoreceptors which leads to the medulla sending impulses to SAN